3D Helical Micromixer Fabricated by Micro Lost‐Wax Casting

Tachibana, Daiki; Matsubara, Ken; Matsuda, Ryosuke; Furukawa, Toshiharu; Maruo, Shoji; Takai, Yoshimi; Fuchiwaki, Ohmi; Ota, Hiroki

doi:10.1002/admt.201900794

Cited by 14 publications

(8 citation statements)

References 45 publications

(89 reference statements)

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“… 26 In view of this, a lost-wax casting method was used to fabricate three-dimensional channels. 11 However, it needs a high temperature to prepare a 3D channel by melting wax, which will affect the channel forming. It is notable that a uniform three-dimensional micromixing mixer is used to process glass by laser processing.…”

Section: Results and Discussionmentioning

confidence: 99%

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Efficient Mixing of Microfluidic Chip with a Three-Dimensional Spiral Structure

et al. 2021

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In this paper, a helical three-dimensional (3D) passive micromixer is presented. A three-dimensional spiral passive micromixer is fabricated through the 3D printing technology and the polymer dissolution technology. The main process is as follows: First of all, a high-impact polystyrene (HIPS) material was used to make a 3D spiral channel mold. Second, the channel mold was dissolved in limonene solvent. The mixing experiment shows that the single helix structure can improve the mixing efficiency to 0.85, compared with the mixing efficiency of 0.78 in the traditional T-shaped two-dimensional (2D)-plane channel. Different screw diameters, screw number structures, and flow rates are used to test the mixing effect. The optimal helical structure is 5 mm, and the flow rate is 2.0 mL/min. Finally, the mixing efficiency of the 3D helical micromixer can reach 0.948. The results show that the three-dimensional helical structure can effectively improve the mixing efficiency.

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Section: Results and Discussionmentioning

confidence: 99%

“…Remarkably, a lost-wax casting method was used to fabricate three-dimensional channels. 11 However, the molten wax preparation channel requires high-temperature conditions, and it is easy to leave residual. The resulting channel is of poor quality.…”

Section: Introductionmentioning

confidence: 99%

Efficient Mixing of Microfluidic Chip with a Three-Dimensional Spiral Structure

et al. 2021

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“…However, this approach is cumbersome. Remarkably, a lost-wax casting method was used to fabricate channels [16]. The preparation of the channel by melting wax material needs to be dissolved at high temperature, so it is easy to leave residue in the channel.…”

Section: Comparison Of Bonding Methods Of Different Materialsmentioning

confidence: 99%

A Method for Manufacturing Flexible Microfluidic Chip Based on Soluble Material

Wang

Chen

Liu

et al. 2021

Journal of Nanomaterials

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In this paper, a novel method for manufacturing flexible microfluidic chips without bonding process is proposed, which combines 3D printing technology and material dissolution technology. The manufacturing process of the microfluidic chip is as follows: a soluble HIPS mold with a preset shape is manufactured by 3D printing and placed in a molten PDMS solution for solidification. Soak in the limonene material to dissolve the mold and form a microchannel in the cured PDMS. Experimental studies have shown that the temperature and concentration of the limonene solution have an important effect on the dissolution rate. A 0.62 cm3 HIPS mold has the fastest dissolution rate at 100°C and 50% concentration. The proposed method provided a new idea for fabricating flexible microfluidic chip. Compared to bonding process, it has the characteristics of not relying on complicated processing conditions and low manufacturing cost.

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“…Yang et al 22 presented a new 3D micromixer design consisting of two layers of spiral channels connected with a vertical erect channel. Several experimental research works are available for the three‐dimensional helical micromixers (TDHM) with circular channels and can be referred to in the literature 23–25 . Two‐dimensional micromixers are easy to fabricate and are generally produced using the traditional soft photolithography technique.…”

Section: Introductionmentioning

confidence: 99%

“…Meanwhile, a similar femtosecond laser irradiation along with chemical etching known as the FLICE technology was used by Liu et al 24 in their investigation to examine the passive mixing in TDHM having a circular cross‐section and a separate glass PDMS packaging was applied to integrate and connect the device with external microchannels and circuits. Recent work of Tachibana et al 23 proposes a novel method to fabricate TDHM using the lost wax casting, which is a feasible method, and no harmful or poisonous gas was used to flush out the melted wax from the device, instead water was employed for the task. The mold to make the microchannel was produced using the high‐resolution 3D‐printing made up of wax‐resin saving production time and increasing the integrability of the micromixer.…”

Section: Introductionmentioning

confidence: 99%

Numerical investigation of the performance of 3D‐helical passive micromixer with Newtonian fluid and non‐Newtonian fluid blood

Tokas

Zunaid

Ansari

2020

Asia-Pacific J Chem Eng

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Mixing at microscales is purely governed by the diffusion mass transport phenomenon, which is a time‐consuming process requiring a prolonged length of the microchannel to obtain desired results. The present study proposes a novel three‐dimensional helical micromixer (TDHM) with a rectangular cross‐section to achieve splendid mixing performance within a short distance contrary to the simple T‐micromixer (STM). A thorough numerical investigation of mixing performance and fluid flow patterns has been conducted using the continuity, species transport, and the Navier–Stokes equations with Newtonian and non‐Newtonian fluid at a wide range of Reynolds number (0.2–320) and mass flow rate (0.00005–0.091 kg/h), respectively. Blood is selected as the non‐Newtonian fluid, and its rheological characteristics are numerically captured by implementing the Carreau–Yasuda model, whereas water is used to study mixing with the Newtonian fluid. At Re = 2, the mixing index of TDHM is 40. 5% more than that of the STM with water as the working fluid, whereas for blood, it is 34.3%, and thus, it was concluded that the TDHM gives much better performance at much less axial distance than that of the STM at all values of the Reynolds number and flow rates considered in the study. Therefore, TDHM can be utilized for various biomedical, chemical, and biochemical applications.

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3D Helical Micromixer Fabricated by Micro Lost‐Wax Casting

Cited by 14 publications

References 45 publications

Efficient Mixing of Microfluidic Chip with a Three-Dimensional Spiral Structure

Efficient Mixing of Microfluidic Chip with a Three-Dimensional Spiral Structure

A Method for Manufacturing Flexible Microfluidic Chip Based on Soluble Material

Numerical investigation of the performance of 3D‐helical passive micromixer with Newtonian fluid and non‐Newtonian fluid blood

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