3D and 4D Printing in Digital Healthcare

Awad, Atheer; Basit, Abdul W.

doi:10.1007/978-3-031-34119-9_1

Cited by 3 publications

(1 citation statement)

References 131 publications

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“…The concept of '3D printing' was first introduced in the early 1980s with the invention of stereolithography by Hideo Kodama [5]. The pursuit of prescribing more tailored medications according to individual patient conditions, genetic characteristics and physical states has become a shared goal among both patients and medical practitioners [6,7]. Yet, traditional pharmaceutical manufacturing processes often lack adaptability [8].…”

Section: Introductionmentioning

confidence: 99%

In Vitro Profile of Hydrocortisone Release from Three-Dimensionally Printed Paediatric Mini-Tablets

Protopapa,

Siamidi,

Kolipaka

et al. 2024

Pharmaceutics

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Three-dimensional (3D) printing is quickly being adopted in pharmaceutics due to the many advantages it offers, including treatment, adaptability, the reduction in waste and the accelerated development of new formulations. In this study, micro-extrusion printing was implemented for the production of modified-release hydrocortisone (HCT) mini-tablets for paediatric patients. For the developed formulations, Gelucire® 44/14 and Precirol® ATO 5 were used as the main inks at three different ratios: 70%/30%, 60%/40% and 50%/50%, respectively. The printing parameters (temperature and pressure) were altered accordingly for each ratio to achieve printability. The printed mini-tablets exhibited excellent printing quality, featuring consistent layer thicknesses and smooth surfaces. Dissolution tests were performed, and the results indicated a successful modified release of HCT from the mini-tablets. In summary, micro-extrusion exhibited favourable processing abilities for powder blends, facilitating quick printing and the fabrication of potential personalized dosages.

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Section: Introductionmentioning

confidence: 99%

In Vitro Profile of Hydrocortisone Release from Three-Dimensionally Printed Paediatric Mini-Tablets

Protopapa,

Siamidi,

Kolipaka

et al. 2024

Pharmaceutics

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Forging a Personalised Path: 3D Printing’s Role in Healthcare Transformation

Awad,

Basit,

Gaisford

et al. 2023

AAPS Advances in the Pharmaceutical Sciences Series

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Industry 4.0

Sindiramutty,

Jhanjhi,

Tan

et al. 2024

Advances in Logistics, Operations, and Management Science

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The advent of Industry 4.0, characterized by the integration of digital technologies into industrial processes, has ushered in a transformative era for manufacturing and beyond. This chapter delves into the future trends and research directions that will shape the landscape of Industry 4.0 in the coming years. One prominent trend is the continued proliferation of the internet of things (IoT) and its convergence with artificial intelligence (AI). As IoT devices become more interconnected and intelligent, they will enable real-time data analysis, predictive maintenance, and adaptive manufacturing, fostering increased efficiency and cost-effectiveness across industries. Moreover, the rise of edge computing is set to redefine data processing and analytics. The deployment of powerful computing resources closer to the data source promises reduced latency and enhanced decision-making capabilities, particularly critical in applications like autonomous manufacturing and remote robotics.

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3D and 4D Printing in Digital Healthcare

Cited by 3 publications

References 131 publications

In Vitro Profile of Hydrocortisone Release from Three-Dimensionally Printed Paediatric Mini-Tablets

In Vitro Profile of Hydrocortisone Release from Three-Dimensionally Printed Paediatric Mini-Tablets

Forging a Personalised Path: 3D Printing’s Role in Healthcare Transformation

Industry 4.0

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