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Diterpenoid alkaloids

“…6 Bessonova and Saidkhodzhaeva listed the hetisine-type C 20 -diterpenoid alkaloids isolated up to 1998. 7 Wang and Liang have contributed a comprehensive review covering the classification, distribution and occurrence, biosynthesis, spectroscopy, chemical reaction and stereochemistry, and pharmacological activity of the C 20 -diterpenoid alkaloids. 8 In this review, a new system of classification for C 20 -diterpenoid alkaloids was proposed, and it was also suggested that the diterpenoid alkaloids be classified into three categories: the C 18 -, C 19 -, and C 20 -diterpenoid alkaloids.…”

Preparative isolation and purification of two new isomeric diterpenoid alkaloids from Aconitum coreanum by high-speed counter-current chromatography

“…The 1 H NMR spectrum of 1 and 2 exhibited 25 proton signals, it indicated protons characteristic signals for one Me (H-C 18 ), one C = CH 2 (H-C 17 ), one CH (H-C 20 ), and one CH 2 (H-C 19 ) group. Signals for Nmethyl, MeO and aromatic ring are absent suggesting that there is no oxazolidine ring in the C 20 skeleton, it can infer that they are C 20 hetisine alkaloids [14].…”

Chemistry and biological activities of hetisine-type diterpenoid alkaloids

“…Besides, Bessonova and Saidkhodzhaeva listed 107 hetisine-type C 20 -DAs that had been isolated up to 1998. 104 During the past two decades, a number of new hetisine-type DAs have been discovered, and their bioactivities were also studied. Hence, this review was prepared to summarize the structural features and biological activities of natural hetisine-type DAs, intending to provide a complete overview of the existing knowledge of the chemical structures and biological properties of hetisine-type DAs, which will facilitate further research and exploitation of these types of compounds.…”