396 Current Practice Regarding the use of Humidified High Flow Nasal Cannulae (HHFNC) in UK Neonatal Units

The clinical effectiveness and cost-effectiveness of heated humidified high-flow nasal cannula compared with usual care for preterm infants: systematic review and economic evaluation

“…The wide variety of indications reported in studies included in systematic reviews, 31,36 surveys 28,29,40,41 and guidelines 20,42 support the need for updated evidence of the effectiveness of HHHFNC for a variety of indications, not simply following ventilation. Although a recent meta-analysis has been published examining extubation failure and the incidence of BPD for HHHFNC compared with NCPAP, 36 there is also the need for a review of the evidence for other relevant outcomes and comparators.…”

Changes in the use of humidified high flow nasal cannula oxygen

“…A systematic review1 of the results of nine trials, which included a total of 1112 infants, however, demonstrated that HHFNC was not superior to other modes of non-invasive ventilation in infants of >28 weeks gestational age. We, therefore, sought to determine whether clinical practice regarding HHFNC had changed since 2012 when all UK units were surveyed2 and also to identify why practitioners preferred HHFNC or continuous positive airway pressure (CPAP).…”

“…In 2012, practitioners from the then 203 UK neonatal units had been contacted 2. Both surveys included questions on the level of neonatal care, the indications for use of HHFNC and the flow rates used.…”