368 Isolated Deep Venous Thrombosis Should be Detectable With Abbreviated Compression Sonography

Abstract

Study Objectives: To evaluate the cost effectiveness and difference in length of stay between early discharge and hospital observation for ED patients diagnosed with lowrisk pulmonary embolism.Methods: Length of stay, encounter costs, and 30-day composite costs were calculated for a prospective cohort of consecutive patients diagnosed with low-risk pulmonary embolism (PESI score <86) at five centers enrolled in the Low-risk PE (LoPE) study. Patients were observed in either the emergency department (EDO) or in the hospital under observation status (HO) and underwent both formal echocardiography and deep venous thrombosis ultrasound. Patients were initiated on FDA-approved therapeutic anticoagulation, were seen by a physician specializing in thrombosis, and had outpatient follow-up scheduled prior to discharge. Patients were also followed for a composite clinical outcome of 90-day all-cause mortality, recurrent PE or DVT, and major bleeding as previously described.