353. a Patient With Eosinophilic Granulomatosis With Polyangiitis Treated Only With Mepolizumab and Intravenous Immunoglobulin

Tamaki, Hiromichi; Ikeda, Yukihiko; Fukui, Sho; Sawada, Haruki; Kitada, Ayako; Kawato, Rui; Suda, Michael; Yanaoka, Haruyuki; Rokutanda, Ryo; Shimizu, Hiroki; Tsuda, Tokutaro; Kishimoto, Mitsumasa; Yamaguchi, Kensei; Okada, Masato

doi:10.1093/rheumatology/kez063.077

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Mcv: Motor Nerve Conduction Velocity Scv: Sensory Nerve Cond...1

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2023

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“…Therefore, we attribute these improvements to mepolizumab. Although there has been one report of induction remission therapy for EGPA with a combination of mepolizumab and IVIG (19), no report exists concerning remission induction with mepolizumab monotherapy. To our knowledge, this is the first report of remission induction with mepolizumab monotherapy.…”

Section: Mcv: Motor Nerve Conduction Velocity Scv: Sensory Nerve Cond...mentioning

confidence: 99%

Anti-neutrophil Cytoplasmic Antibody-negative Eosinophilic Granulomatosis with Polyangiitis Complicated with Peripheral Neuropathy that Underwent Remission Induction with Mepolizumab Monotherapy

et al. 2023

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A 72-year-old woman was admitted to our hospital with numbness in her lower extremities and hypereosinophilia. She was diagnosed with eosinophilic granulomatosis with polyangiitis (EGPA). On admission, she was suspected of being complicated with pneumonia and sepsis; therefore, treatment with mepolizumab monotherapy was begun, resulting in partial improvement. After the possibility of a complicating infection was ruled out, corticosteroids were initiated, followed by intravenous gamma globulin therapy. Although the induction of remission of EGPA with mepolizumab monotherapy is not usually recommended, induction with mepolizumab monotherapy may be an option in terms of safety and clinical efficacy in some cases.

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Section: Mcv: Motor Nerve Conduction Velocity Scv: Sensory Nerve Cond...mentioning

confidence: 99%

Anti-neutrophil Cytoplasmic Antibody-negative Eosinophilic Granulomatosis with Polyangiitis Complicated with Peripheral Neuropathy that Underwent Remission Induction with Mepolizumab Monotherapy

et al. 2023

View full text Add to dashboard Cite

show abstract

353. a Patient With Eosinophilic Granulomatosis With Polyangiitis Treated Only With Mepolizumab and Intravenous Immunoglobulin

Cited by 1 publication

References 0 publications

Anti-neutrophil Cytoplasmic Antibody-negative Eosinophilic Granulomatosis with Polyangiitis Complicated with Peripheral Neuropathy that Underwent Remission Induction with Mepolizumab Monotherapy

Anti-neutrophil Cytoplasmic Antibody-negative Eosinophilic Granulomatosis with Polyangiitis Complicated with Peripheral Neuropathy that Underwent Remission Induction with Mepolizumab Monotherapy

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