Physical activity in management of persons with obesity

Oppert, Jean‐Michel; Bellicha, Alice; Ciangura, C.

doi:10.1016/j.ejim.2021.04.028

Cited by 40 publications

(30 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The treatment is manifold and characterized by high dropout rates and poor long-term efficacy. Current therapeutic choices provide a multistep progression that includes dietary and behavioral changes, physical activity, drug treatment, up to bariatric surgery in selected cases [3][4][5][6]. However, although bariatric Cristina Segura-Garcia, Matteo Aloi and Marianna Rania are joint first authors.…”

Section: Introductionmentioning

confidence: 99%

Development, validation and clinical use of the Eating Behaviors Assessment for Obesity (EBA-O)

et al. 2022

View full text Add to dashboard Cite

Introduction Obesity is a major health problem with an increasing risk of mortality, associated with comorbidities and high rates of dropout. Research demonstrated that pathological eating behaviors could help to phenotype obese patients thus tailoring clinical interventions. Therefore, our aim was to develop (study 1), validate (study 2), and test in a clinical setting (study 3) the Eating Behaviors Assessment for Obesity (EBA-O). Method Study 1 included the exploratory factor analysis (EFA) and McDonald's ω in a general population sample (N = 471). Study 2 foresaw the confirmatory factor analysis (CFA) and convergent validity in 169 participants with obesity. Study 3 tested the capability of the EBA-O to characterize eating behaviors in a clinical sample of 74 patients with obesity. Results Study 1. EFA identified five factors (i.e., food addiction, night eating, binge eating, sweet eating, and prandial hyperphagia), explaining 68.3% of the variance. The final EBA-O consisted of 18 items. McDonald's ω ranged between 0.80 (hyperphagia) and 0.92 (binge eating), indicating very good reliability. Study 2. A second-order five-factor model, through CFA, showed adequate fit: relative chi-square (χ 2 /df) = 1.95, CFI = 0.93, TLI = 0.92, RMSEA = 0.075, and SRMR = 0.06, thus suggesting the appropriateness of the EBA-O model. Significant correlations with psychopathological questionnaires demonstrated the convergent validity. Study 3. Significant associations between EBA-O factors and emotional-related eating behaviors emerged. ConclusionThe EBA-O demonstrated to be a reliable and easy-to-use clinical tool to identify pathological eating behaviors in obesity, particularly useful for non-experts in eating disorders. Level of evidence Level V, descriptive research.

show abstract

Section: Introductionmentioning

confidence: 99%

Development, validation and clinical use of the Eating Behaviors Assessment for Obesity (EBA-O)

et al. 2022

View full text Add to dashboard Cite

show abstract

Section: Nrg4 and Obesitymentioning

confidence: 99%

“…Physical activity is a well-recognized lifestyle intervention to combat obesity ( Oppert et al, 2021 ). Nrg4 levels in men with obesity were significantly increased by 12 weeks of resistance training (conventional, circular, and interval) ( Alizadeh et al, 2021 ), suggesting that Nrg4 may be involved in exercise-induced weight loss.…”

Section: Introductionmentioning

confidence: 99%

Neuregulin 4 as a novel adipokine in energy metabolism

Liu

Chen

2023

Front. Physiol.

View full text Add to dashboard Cite

Adipose tissue has been shown to play a key role in energy metabolism and it has been shown to regulate metabolic homeostasis through the secretion of adipokines. Neuregulin 4 (Nrg4), a novel adipokine secreted mainly by brown adipose tissue (BAT), has recently been characterized as having an important effect on the regulation of energy homeostasis and glucolipid metabolism. Nrg4 can modulate BAT-related thermogenesis by increasing sympathetic innervation of adipose tissue and therefore has potential metabolic benefits. Nrg4 improves metabolic dysregulation in various metabolic diseases such as insulin resistance, obesity, non-alcoholic fatty liver disease, and diabetes through several mechanisms such as anti-inflammation, autophagy regulation, pro-angiogenesis, and lipid metabolism normalization. However, inconsistent findings are found regarding the effects of Nrg4 on metabolic diseases in clinical settings, and this heterogeneity needs to be further clarified by future studies. The potential metabolic protective effect of Nrg4 suggests that it may be a promising endocrine therapeutic target.

show abstract

“…Obesity increases the risk of many health problems, including T2D, metabolic syndrome, CVDs, and cancer, and therefore leads to higher mortality (Aune et al, 2016), (Global BMI Mortality Collaboration Di Angelantonio et al, 2016). Physical exercise prevents obesity, reduces visceral fat and maintains body weight (Oppert et al, 2021), (Swift et al, 2018), (Villareal et al, 2017). Drosophila has become an excellent model for metabolic and diet-related diseases due to its powerful genetic tools and stable reproducible phenotype (Birse et al, 2010), (Musselman and Kühnlein, 2018).…”

Section: Development Of Drosophila Exercise Models In Obesity-related...mentioning

confidence: 99%

Drosophila exercise, an emerging model bridging the fields of exercise and aging in human

Ding

Li²,

Zheng³

2022

Front. Cell Dev. Biol.

View full text Add to dashboard Cite

Exercise is one of the most effective treatments for the diseases of aging. In recent years, a growing number of researchers have used Drosophila melanogaster to study the broad benefits of regular exercise in aging individuals. With the widespread use of Drosophila exercise models and the upgrading of the Drosophila exercise apparatus, we should carefully examine the differential contribution of regular exercise in the aging process to facilitate more detailed quantitative measurements and assessment of the exercise phenotype. In this paper, we review some of the resources available for Drosophila exercise models. The focus is on the impact of regular exercise or exercise adaptation in the aging process in Drosophila and highlights the great potential and current challenges faced by this model in the field of anti-aging research.

show abstract

Physical activity in management of persons with obesity

Cited by 40 publications

References 42 publications

Development, validation and clinical use of the Eating Behaviors Assessment for Obesity (EBA-O)

Development, validation and clinical use of the Eating Behaviors Assessment for Obesity (EBA-O)

Neuregulin 4 as a novel adipokine in energy metabolism

Drosophila exercise, an emerging model bridging the fields of exercise and aging in human

Contact Info

Product

Resources

About