A case of organophosphate poisoning with intermediate syndrome and acute pancreatitis – A rare complication

Pesticides will be utilized to manage pests that are important to agriculture and health care, and they will continue to be necessary for the future related to food security and prevention and control. Pesticides are unlikely to be phased out in the foreseeable future, but they should be handled with prudence. The majority of pesticides are hazardous to humans and can cause serious health problems which lead to death. During chemical spraying, skin contact accounts for about all of the body exposure. Contamination, such as for local farmers in open vegetable farming or pesticide industry employees, may result in direct exposure. Indirect exposure can occur through dietary goods such as food and drinking water, as well as the usage of repellents in homes. Some neurotoxic effects are immediately apparent, while others might take months or even years to appear. A variety of variables, including the toxin’s characteristics and the dosage a person, is exposed to, determine the consequences of neurotoxicity. Amyotrophic Lateral Sclerosis, Intermediate syndrome, Parkinson’s disease, and Alzheimer’s disease are diseases that highly damage the mental health and the neural health of a person. This review is mainly focused on types of pesticides, route of pesticide entry in body, their effect on human health, and how these pesticides induce neural diseases.

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“…The results of the meta-analysis revealed that pesticide exposure may raise the incidence of ALS [Figure 4]. [48][49][50][51][52][53][54][55]…”

Section: Amyotrophic Lateral Sclerosismentioning

confidence: 99%

Effect of Pesticides on Nervous System or Neural Health

Chavan¹,

Mehta

2022

APJHS

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“…OPs are commonly used for farming in India, which is mostly agrarian. Globally, pesticide poisoning from OPs is a serious occupational hazard worldwide, accounting for more than 80% of pesticide-related deaths and hospitalizations [ 5 ]. Because India is an agriculturally based country, OPs remain the primary crop protection and pest control chemical [ 6 ].…”

Section: Introductionmentioning

confidence: 99%

Resurgence to Life: A Case Report on Inpatient Rehabilitation in Organophosphate Poisoning Followed by Intermediate Syndrome

Bhakaney,

Yadav,

Nagore

et al. 2023

Cureus

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Organophosphate poisoning (OPP) results from the occupational, accidental, or suicidal intake of organophosphate pesticides (OPs). There is a huge limitation in the available literature on OPP cases and the role of physiotherapy in such cases. We report a case of a 33-year-old farmer, found in a state of ingested insecticide and admitted to the emergency department. The patient had two to three episodes of vomiting, associated with continuous tremors in his hands and legs. Immediately infused with atropine, the patient's general condition deteriorated, and he was intubated with an endotracheal tube. With the signs of long-term intubation, a tracheostomy was done. A respiratory therapy consult was taken for indications of intermediate syndrome and to achieve early weaning. The patient's referral was received in view of the long-term requirement of bronchial hygiene and the need for early ambulation as well as psychological support. Informed consent was taken from the family prior to the commencement of the treatment. Respiratory therapy interventions included body positioning, bronchial hygiene techniques, chest proprioceptive neuromuscular facilitation (PNF) techniques, and mobility exercises to achieve early ambulation. Physiotherapists have the appropriate training, knowledge, and skills to deliver the exercise components and help patients return to their activities of daily living. Significant levels of improvement have been seen in the general condition of the patient. The overall functioning of the patient's health was seen as improved on the scales of consciousness, early mobility in the step-down unit, and quality of life.

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Intermediate syndrome following organophosphate poisoning: A case report in a low resource and poor socio‐economic setting

Lageju

Neupane

Jaiswal

et al. 2022

Clinical Case Reports

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According to World Health Organization (WHO), approximately 3 million pesticide poisoning occurs worldwide and more than 40,000 deaths per year. 1 Among pesticide poisoning, organophosphate(OP) poisoning is one of the most common causes of poisoning in developing countries. 2 Based on the onset of the signs and symptoms of OP poisoning, it is categorized into acute (minutes to 24 h), delayed (24 h-2 weeks), and late (beyond 2 weeks). 3 The activity of muscarinic and nicotinic receptors causes acute onset symptoms. Muscarinic symptoms include salivation, lacrimation, urination, defecation, gastric cramps, emesis, bradycardia, hypotension, miosis, and bradycardia. Weakness, fasciculation, cramps, and paralysis are all nicotinic symptoms. The delayed onset nicotinic symptoms are intermediate syndrome. 4 Intermediate syndrome (IMS) usually develops after 2-4 days of oral OP poisoning. It occurs in around 20% of OP poisoning cases. The paralysis of respiratory muscles and paralysis of the peripheral

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A case of organophosphate poisoning with intermediate syndrome and acute pancreatitis – A rare complication

Cited by 5 publications

References 8 publications

Effect of Pesticides on Nervous System or Neural Health

Effect of Pesticides on Nervous System or Neural Health

Resurgence to Life: A Case Report on Inpatient Rehabilitation in Organophosphate Poisoning Followed by Intermediate Syndrome

Intermediate syndrome following organophosphate poisoning: A case report in a low resource and poor socio‐economic setting

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