Author Correction: RADICL-seq identifies general and cell type–specific principles of genome-wide RNA-chromatin interactions

Bonetti, Alessandro; Federico, Antonella; Hashimoto, Kosuke; Pascarella, Giovanni; Gimenez, Juliette; Roos, Leonie; Nash, Alex J.; Ghilotti, Marco; Cameron, Christopher J.F.; Valentine, Matthew; Medvedeva, Yulia A.; Noguchi, Shuhei; Agirre, Eneritz; Kashi, Kaori; Samudyata, S.; Luginbühl, Joachim; Cazzoli, Riccardo; Agrawal, Saumya; Luscombe, Nicholas M.; Blanchette, Mathieu; Kasukawa, Takeya; Hoon, Michiel de; Arner, Peter; Lenhard, Boris; Plessy, Charles; Castelo‐Branco, Gonçalo; Orlando, Valerio

doi:10.1038/s41467-021-23542-w

Cited by 4 publications

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Unveiling the specific interactions of lncRNAs with either DNA sequences, other transcripts, and/or proteins may provide important indications for their possible cellular function. Therefore, implementing novel methodologies such as ChIRP-seq [ 140 ] and RADICL-seq [ 141 ] together with ChIRP-MS [ 142 ] and CLIP [ 105 , 143 ] could be utilized to uncover their functions in P . falciparum .…”

Section: How Do Lncrnas Regulate Gene Expression?mentioning

confidence: 99%

Emerging biology of noncoding RNAs in malaria parasites

Simantov¹,

Goyal²,

Dzikowski³

2022

PLoS Pathog

View full text Add to dashboard Cite

In eukaryotic organisms, noncoding RNAs (ncRNAs) have been implicated as important regulators of multifaceted biological processes, including transcriptional, posttranscriptional, and epigenetic regulation of gene expression. In recent years, it is becoming clear that protozoan parasites encode diverse ncRNA transcripts; however, little is known about their cellular functions. Recent advances in high-throughput “omic” studies identified many novel long ncRNAs (lncRNAs) in apicomplexan parasites, some of which undergo splicing, polyadenylation, and encode small proteins. To date, only a few of them are characterized, leaving a big gap in our understanding regarding their origin, mode of action, and functions in parasite biology. In this review, we focus on lncRNAs of the human malaria parasite Plasmodium falciparum and highlight their cellular functions and possible mechanisms of action.

show abstract