Publisher Correction: Analysis of global human gut metagenomes shows that metabolic resilience potential for short-chain fatty acid production is strongly influenced by lifestyle

Jacobson, David P.; Honap, Tanvi P.; Ozga, Andrew T.; Méda, Nicolas; Kagoné, Thérèse; Carabin, Hélène; Spicer, Paul; Tito, Raúl Y.; Obregón-Tito, Alexandra J.; Reyes, Luis Marin; Troncoso-Corzo, Luzmila; Guija-Poma, Emilio; Sankaranarayanan, Krithivasan; Lewis, Cecil M.

doi:10.1038/s41598-021-89719-x

Cited by 1 publication

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…S6). The variations in prevalence of these species in human populations could potentially be linked to dietary disparities between individuals in industrialized and nonindustrialized societies ( 26 , 27 ), as well as human activities that affect microbial diversity such as the use of antibiotics ( 28 ). Dietary fiber intake may be a major contributing factor given its close association with the prevalence and abundance of these species.…”

Section: Fiber-degrading Bacterial Species Prevalence In Nonindustria...mentioning

confidence: 99%

Cryptic diversity of cellulose-degrading gut bacteria in industrialized humans

Moraïs,

Winkler,

Zorea

et al. 2024

Science

View full text Add to dashboard Cite

Humans, like all mammals, depend on the gut microbiome for digestion of cellulose, the main component of plant fiber. However, evidence for cellulose fermentation in the human gut is scarce. We have identified ruminococcal species in the gut microbiota of human populations that assemble functional multienzymatic cellulosome structures capable of degrading plant cell wall polysaccharides. One of these species, which is strongly associated with humans, likely originated in the ruminant gut and was subsequently transferred to the human gut, potentially during domestication where it underwent diversification and diet-related adaptation through the acquisition of genes from other gut microbes. Collectively, these species are abundant and widespread among ancient humans, hunter-gatherers, and rural populations but are rare in populations from industrialized societies thus indicating potential disappearance in response to the westernized lifestyle.

show abstract

Section: Fiber-degrading Bacterial Species Prevalence In Nonindustria...mentioning

confidence: 99%