Fragmented QRS as a marker of coronary atherosclerosis severity evaluated by the Gensini score

Fedulaev, Yu. N.; Макарова, И. В.; Pinchuk, T. V.

doi:10.1016/j.ancard.2021.03.001

Cited by 2 publications

(2 citation statements)

References 19 publications

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“…Furthermore, we demonstrated that QRS fragmentation in V5 or V6 was extremely rare. Consistently, QRS fragmentation in lateral leads has been reported to be associated with the presence of structural heart disease and sudden cardiac death [31,32]. Thus, the detection of QRS fragmentation in V5 or V6 in a presumably healthy individual could reasonably indicate a diagnostic work up for the exclusion of cardiac disease.…”

Section: Distribution Of Qrs Fragmentation In the Leads Of Electrocar...mentioning

confidence: 73%

Physiological Changes in QRS Fragmentation in Athletes and Nonathletes without Cardiac Disease

Christou,

Christou

et al. 2024

JCM

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QRS fragmentation has not been linked with increased mortality in individuals without known cardiac disease. We aimed to investigate the physiological determinants of QRS fragmentation in individuals without cardiac disease. Methods: Study participants were 163 (54 athletes, 109 nonathletes) asymptomatic individuals with QRS fragmentation but without cardiac disease. QRS fragmentation was assessed in the supine position after deep inspiration or standing up and during exercise. The changes in QRS fragmentation were evaluated over a median follow-up period of 2.3 (0.8–4.9) years. Results: The most common lead with QRS fragmentation was III (63.0% in athletes, 61.5% in nonathletes), immediately followed by V1 (50.0%) and aVF (42.6%) in athletes and aVF (55.0%) in nonathletes. QRS fragmentation in V1 was more frequent in athletes compared to nonathletes (p < 0.001). Among athletes, the presence of QRS fragmentation in V1 could be independently predicted by increased RVOTproxi (right ventricular outflow tract proximal diameter indexed to body surface area) (p < 0.001). Among individuals with QRS fragmentation in V1, deep inspiration resulted in disappearance of QRS fragmentation more frequently in nonathletes compared to athletes (100% vs. 20%, p = 0.003). Deep inspiration resulted in disappearance of QRS fragmentation in aVF (p < 0.001). The presence of QRS fragmentation in II or aVF was associated with increased body mass index (BMI) (p = 0.003). Among athletes without QRS fragmentation in V1 at baseline, the appearance of QRS fragmentation in V1 at the end of follow-up was associated with greater training age (p = 0.034). Among individuals with QRS fragmentation in aVF at baseline, the disappearance of QRS fragmentation in aVF at the end of follow-up was associated with greater reduction in BMI (p = 0.008). Conclusions: The characteristic feature of QRS fragmentation in athletes was the presence of QRS fragmentation in V1, which was associated with RVOTproxi. The persistence of QRS fragmentation in V1 after deep inspiration could serve as a specific marker of exercise-training-related cardiac adaptation. The presence of QRS fragmentation in the leads of the frontal plane was influenced by BMI and respiration phase.

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Section: Distribution Of Qrs Fragmentation In the Leads Of Electrocar...mentioning

confidence: 73%

Physiological Changes in QRS Fragmentation in Athletes and Nonathletes without Cardiac Disease

Christou,

Christou

et al. 2024

JCM

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“…Toraman et al, found fQRS to be a predictor of subclinical atherosclerosis in chronic kidney disease patients by looking at fQRS 24 . Fedulaev et al, found that the presence of fQRS in lateral derivations showed that it could be a non-invasive marker of severe coronary atherosclerosis 25 . Karabakan et al, found that fQRS could provide a comprehensive diagnostic approach for underlying cardiovascular diseases 26 .…”

Section: Discussionmentioning

confidence: 99%

Association between uterine leiomyoma and fragmented QRS waves: a prospective case-control study

Tatlici,

Cetin,

Korpe

et al. 2024

Rev. Assoc. Med. Bras.

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OBJECTIVE:The aim of this study was to evaluate the relationship between uterine leiomyoma and fragmented QRS, a non-invasive indicator of cardiovascular risk and myocardial ischemia, in women with uterine leiomyoma. METHODS: In this prospective case-control study, a total of 47 patients diagnosed with uterine leiomyoma (case group) and 47 healthy individuals without uterine leiomyoma (control group) who had undergone bilateral tubal ligation surgery were included. Various demographic, clinical, and laboratory parameters and the presence of fragmented QRS were recorded. RESULTS: The leiomyoma group showed significantly higher body mass index (27.46±2.18 vs. 25.9±2.87 kg/m 2 , p=0.005) and waist circumference (91.34±9.30 vs. 84.97±9.3 cm, p=0.001) compared with the control group. Uterine volumes were also significantly higher in the leiomyoma group (235.75±323.48 vs. 53.24±12.81 mm 3 , p<0.001). The presence of fragmented QRS was detected in 18.1% of the patients. Multiple regression analysis identified age, fasting blood glucose value, and the presence of fragmented QRS as independent risk factors for the presence of leiomyoma. CONCLUSION: This study provides valuable insights into the relationship between uterine leiomyoma and fragmented QRS. The presence of fragmented QRS was identified as an independent risk factor for the presence of leiomyoma. Further research is needed to better understand the underlying mechanisms connecting uterine leiomyoma and cardiovascular health.

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Fragmented QRS as a marker of coronary atherosclerosis severity evaluated by the Gensini score

Cited by 2 publications

References 19 publications

Physiological Changes in QRS Fragmentation in Athletes and Nonathletes without Cardiac Disease

Physiological Changes in QRS Fragmentation in Athletes and Nonathletes without Cardiac Disease

Association between uterine leiomyoma and fragmented QRS waves: a prospective case-control study

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