Gel immersion endoscopic submucosal dissection using a novel gel product for a duodenal epithelial tumor

Tashima, Tomoaki; Miyaguchi, Kazuya; Terada, Rie; Mashimo, Yumi; Tanisaka, Yuki; Kawasaki, Tomonori; Ryozawa, Shomei

doi:10.1055/a-1443-4796

Cited by 5 publications

(8 citation statements)

References 5 publications

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“…Recently, we have been actively performing gel immersion ESD in organs with a narrow lumen where gel immersion is easy. [18][19][20] For mucosal defect closure, OTSC placement is not routinely required. Previously, we reported the potential of using OTSCs to prevent AEs after duodenal ESD.…”

Section: Discussionmentioning

confidence: 99%

Successful endoscopic resection by using gel immersion and the technique of endoscopic papillectomy for a tumor adjacent to the papilla of Vater

Tashima¹,

Ogawa²,

Kawasaki³

et al. 2022

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Section: Discussionmentioning

confidence: 99%

Successful endoscopic resection by using gel immersion and the technique of endoscopic papillectomy for a tumor adjacent to the papilla of Vater

Tashima¹,

Ogawa²,

Kawasaki³

et al. 2022

VideoGIE

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“…A literature search for “Gel immersion endoscopy” in PubMed revealed nine cases published over 10 years 1‐3,5‐10 . Of these, seven were reported in 2021.…”

Section: Discussionmentioning

confidence: 99%

“…GIE provides good outcomes in various conditions, including gastrointestinal bleeding, colonic diverticular bleeding, and rectal ulcers. It is applied to endoscopic treatments such as EMR and endoscopic submucosal dissection 5‐9 . Therefore, the use of the new GIM for endoscopic diagnostics is expected in the near future.…”

Section: Discussionmentioning

confidence: 99%

Endoscopic hemostasis using gel immersion endoscopy for duodenal ulcer and a sigmoid colon polyp: A novel gel injection method

et al. 2022

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Gel immersion endoscopy (GIE) has gained prominence for securing a good visual field. Traditionally, OS‐1 jelly (Otsuka Pharmaceutical Factory) has been used for GIE. However, due to the presence of electrolytes, it is unsuitable for endoscopic hemostasis using a monopolar device. Therefore, VISCOCLEAR (Otsuka Pharmaceutical Factory), a new gel that does not contain electrolytes, has been developed. Moreover, unlike water or saline, VISCOCLEAR does not readily mix with blood, making it effective in visualizing gastrointestinal bleeding. We report two cases in which GIE was performed using a novel gel injection method.

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“…The gel for this method needs to be of an appropriate viscoelasticity to ensure injectability via the accessory channel and the ability to secure the visual field. An electrolyte-free gel dedicated to this method "VISCOCLEAR" was launched in Japan in October 2020 [3] and its efficacy was reported in clinical practice [4][5][6][7][8][9]. "VISCOCLEAR" is a gel with a three-dimensional network structure due to the molecular interaction of xanthan gum and locust bean gum.…”

Section: Introductionmentioning

confidence: 99%

Factors contributing to changes in viscosity and flow rate of a dedicated gel for gel immersion endoscopy

et al. 2022

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Background and study aims Gel immersion endoscopy is a novel technique for securing the visual field during endoscopy. Clinical application of a dedicated gel for this technique with an appropriate viscosity to prevent mixing with blood and its efficacy was reported. The aim of this study was to evaluate changes in gel viscosity and flow rate under different conditions. Methods The viscosity of the gel after injection and flow rate were measured under various conditions changing the injection route and method. Gel viscosity was measured at 25, 10, and 4 °C. Results A decrease in gel viscosity was found when the gel was injected via the water jet channel compared to the accessory channel. The flow rate and decrease in viscosity of the gel injected via the water jet channel were 220 mL/min and 63.2 %, while when injected via the accessory channel with a clip device inserted were 560 mL/min and 35.8 %. When the gel was kept at a low temperature, the viscosity increased. Conclusions Gel injection via the accessory channel should be the first choice for efficient use considering the viscosity and flow rate.

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Gel immersion endoscopic submucosal dissection using a novel gel product for a duodenal epithelial tumor

Cited by 5 publications

References 5 publications

Successful endoscopic resection by using gel immersion and the technique of endoscopic papillectomy for a tumor adjacent to the papilla of Vater

Successful endoscopic resection by using gel immersion and the technique of endoscopic papillectomy for a tumor adjacent to the papilla of Vater

Endoscopic hemostasis using gel immersion endoscopy for duodenal ulcer and a sigmoid colon polyp: A novel gel injection method

Factors contributing to changes in viscosity and flow rate of a dedicated gel for gel immersion endoscopy

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