Effect of infusion set replacement intervals on catheter-related bloodstream infections (RSVP): a randomised, controlled, equivalence (central venous access device)–non-inferiority (peripheral arterial catheter) trial

Strategies to prevent central line-associated bloodstream infections in acute-care hospitals: 2022 Update

“…162,163 6. Routine replacement of administration sets not used for blood, blood products, or lipid formulations can be performed at intervals up to 7 days (Quality of Evidence: HIGH) 164 a. The optimal replacement of intermittently used administration sets is unresolved.…”

Harnessing the nursing and midwifery workforce to boost Australia's clinical research impact

“… 2 In Australia, investment in nursing‐ and midwifery‐led research also pays dividends for health care costs and population and health system outcomes, as evidenced from the many research contributions of Australian nurses and midwives over the past decade ( Box ). 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 …”

“…Major savings for the health system Less frequent replacement of infusion sets shown to be safe, reducing national costs by $75 million annually for central venous and peripheral arterial catheters 7 Reduced health care costs ($13 100 less per person) and duration of all‐cause hospital stay (10 days fewer) with home‐based intervention for older patients with chronic heart failure 8 Caseload midwifery proven safe and cost‐effective for women of any risk, saving more than $560 per woman 9 $65 million savings in health care costs and $252 million savings in societal costs from stroke nursing protocols over 5 years 10 …”

“…Less frequent replacement of infusion sets shown to be safe, reducing national costs by $75 million annually for central venous and peripheral arterial catheters 7 …”

Update on prevention of intra-vascular accesses complications

“…They can be safely maintained for up to 7 days but should be changed immediately if they are non-adherent, soiled or moistened. The infusion set should also be changed every 7 days [14]. A new adhesive compound was not able to significantly reduce dressing disruption in ICU [1].…”