Organ integration in kidney transplant patients – Results of a KTx360° substudy

Hennemann, Khira; Bauer-Hohmann, Maximilian; Klewitz, Felix; Tegtbur, Uwe; Pape, Lars; Schiffer, Lena; Schiffer, Mario; Zwaan, Martina de; Nöhre, Mariel

doi:10.1016/j.jpsychores.2021.110464

Cited by 4 publications

(10 citation statements)

References 30 publications

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“…Preserving a positive image of the donor might assuage fears of contamination and ultimately graft rejection. This notion was congruent with recipients' fears of being influenced by the graft, 22 beliefs about having adopted some of the donor's traits, 23 identification of graft failure as their biggest stressor, 24 and sense of protection from graft rejection when they perceive greater similarity between themselves and the donor. 25 Our study adds to this body of research by tying approachavoidance movements together into an optimal distance-regulation mechanism that functions to modulate fears of graft failure.…”

Section: Discussionmentioning

confidence: 78%

The Psychosocial Adjustment of Kidney Recipients in Canada's Kidney Paired Donation Program

Bourkas

Achille

2021

Prog Transpl

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Introduction: Kidney paired donation programs have been implemented globally. The involvement of at least 2 donors in these programs might exacerbate recipients’ debt of gratitude and guilt, worries about the donor's health, and worries about graft failure documented by previous studies. However, there is an absence of research on the psychosocial implications of kidney paired donation. This study aimed to provide an in-depth examination of recipients’ experience of kidney paired donation, with a focus on psychosocial adjustment. Methods/Approach: Individual interviews were conducted with 8 recipients who received a transplant through Canada's Kidney Paired Donation program. Data was analyzed using Interpretative Phenomenological Analysis. Findings: Four themes emerged: (a) an emotionally charged relationship with the known donor, (b) optimal distance regulation in the relationship with the anonymous donor, (c) kidney paired donation as a series of ups and downs, and (d) multilayered gratitude. Discussion: Findings are considered in relation to extant literature. Issues relevant to the transplant community's clinical and research efforts to provide kidney recipients responsive care are discussed.

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Section: Discussionmentioning

confidence: 78%

The Psychosocial Adjustment of Kidney Recipients in Canada's Kidney Paired Donation Program

Bourkas

Achille

2021

Prog Transpl

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“…In the qualitative study of teenagers by Kärrfelt et al [21], three out of 20 recipients (15%) who had received an organ as a child reported DDI. Hennemann et al [34] found a higher prevalence: In their survey, 52.3% reported that they were frequently preoccupied with thoughts regarding the donor.…”

Section: Prevalencementioning

confidence: 86%

“…Other authors stated that sexual orientation also played a role [26,38]. Hennemann et al [34] found that 13.6% of patients had the impression they adopted traits of the donor.…”

Section: Content Of Ddimentioning

confidence: 99%

“…Two studies addressing DDI in the context of kidney transplantation found a prevalence of DDI in kidney transplant recipients [21,34]. In the qualitative study of teenagers by Kärrfelt et al [21], three out of 20 recipients (15%) who had received an organ as a child reported DDI.…”

Section: Prevalencementioning

confidence: 99%

“…As a very direct consequence, Hennemann et al [34] pointed out that thinking about the donor and beliefs about the transfer of traits were positively associated with patient anxiety scores [34].…”

Section: Consequences Of Ddimentioning

confidence: 99%

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Donor and Donation Images (DDI)—A Scoping Review of What We Know and What We Don’t

Laskowski

Brandt

Tigges-Limmer

et al. 2023

JCM

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Organ transplantation is associated with significant physical and psychological burden for the recipients. Qualitative reports indicate that organ recipients develop donor and donation images (DDI)—conceptions of the donor and/or the organ. A deeper understanding of DDI is needed in the care of transplant recipients. To present the current state of knowledge, we searched for and identified DDI-related publications in PubMed and Scopus. Inclusion criteria were (1) studies addressing transplant recipients, and (2) English or German language. Twenty-one studies of individuals with transplanted hearts, lungs, or kidneys were included in this scoping review. Prevalence for DDI ranged from 6% to 52.3%. DDI occurs both before and after transplantation and includes ideas about the donor as well as whether and how the recipient’s personality may be altered by the transplanted organ. Some transplant recipients did indeed report personality changes following transplantation due to the adoption of assumed donor characteristics. One study showed a positive association between the presence of DDI and anxiety scores and one described a coping effect. DDI is understudied and should be systematically assessed to improve care for the vulnerable group of individuals undergoing organ transplantation. Current research gaps and future directions are discussed.

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Expert consensus on clinical trials of human xenotransplantation in China

Huang¹

2022

Health Care Science

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The history of xenotransplantation started in the 19th century. After a few decades of investigation, significant breakthroughs and preclinical milestones have been achieved worldwide. With the recent transplantation of genetically modified porcine kidneys and heart into humans, these ground-breaking achievements have attracted great attention worldwide, in the hope that xenotransplantation might alleviate or even solve the problem of organ shortage. On January 20, 2022, the China Organ Transplantation Development Foundation convened a symposium on "The History, Current Situation and Future of Human Xenotransplantation Clinical Trials," where ways to promote the ethical and sustainable development of xenotransplantation in China were discussed among the participating experts. A formal consensus was reached as the product of the symposium, outlining the expert opinions on scientific, regulatory, and ethical issues of clinical trials of xenotransplantation in China.

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Organ integration in kidney transplant patients – Results of a KTx360° substudy

Cited by 4 publications

References 30 publications

The Psychosocial Adjustment of Kidney Recipients in Canada's Kidney Paired Donation Program

The Psychosocial Adjustment of Kidney Recipients in Canada's Kidney Paired Donation Program

Donor and Donation Images (DDI)—A Scoping Review of What We Know and What We Don’t

Expert consensus on clinical trials of human xenotransplantation in China

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