Risk Factors for Thrombus Formation at Stage 2 Palliation and Its Effect on Long-Term Outcome in Patients With Univentricular Heart

Ono, Masamichi; Kido, Takashi; Burri, Melchior; Anderl, Lisa; Ruf, Bettina; Cleuziou, Julie; Strbad, Martina; Hager, Alfred; Hörer, Jürgen; Lange, Rüdiger

doi:10.1053/j.semtcvs.2021.02.024

Cited by 3 publications

(2 citation statements)

References 33 publications

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“…The INARI FlowTriever device can remove DVT and significantly reduce the risk of bleeding [ 14 ]. Some studies analyzed and studied the causes of DVT and the locations where DVT frequently occurs [ 15 , 16 ]. Other studies have found that DVT can trigger other diseases [ 2 , 17 – 19 ], such as multiple organ embolism, stroke, and acute myocardial infarction.…”

Section: Introductionmentioning

confidence: 99%

Computational Analysis of the Related Factors of Deep Vein Thrombosis (DVT) Formation in Patients Undergoing Hip Fracture Surgery

Zhou

Chen

Zhang

et al. 2022

Evidence-Based Complementary and Alternative Medicine

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A retrospective study was conducted on 51 patients undergoing hip fracture surgery to investigate the factors associated with the formation of deep venous thrombosis (DVT). The independent sample t-test and correlation analysis were used to sort out and analyze the data. The findings are as follows. (1) Different gender samples showed significant differences in the Caprini score and thrombus location. Most DVTs in females are located in the posterior tibial vein and intermuscular veins. The Caprini score of females was significantly higher than that of males. (2) Age displays a positive correlation with DVT, coronary heart disease, hypertension, and different surgical types, respectively. (3) There is a correlation between age and operation duration. (4) Hyperlipidemia and cerebrovascular disease show a positive correlation with DVT. (5) There was a significant negative correlation between the Caprini score and the quantification of D-dimer. This indicates that in this sample, the higher the patients’ Caprini score is, the lower the quantitation of D-dimer will be. (6) Hyperlipidemia and cardiac insufficiency show a positive correlation with cerebrovascular disease. Patients with hyperlipidemia and cardiac insufficiency may also suffer from cerebrovascular diseases.

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Section: Introductionmentioning

confidence: 99%

Computational Analysis of the Related Factors of Deep Vein Thrombosis (DVT) Formation in Patients Undergoing Hip Fracture Surgery

Zhou

Chen

Zhang

et al. 2022

Evidence-Based Complementary and Alternative Medicine

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show abstract

“…Because we actually experience no early mortality after stage III Fontan palliation, concerns have been focused on the indication, timing, and postoperative management of stage II palliation by means of bidirectional cavopulmonary shunt (BCPS) procedure in patients with functional single ventricle physiology. 1 , 2 , 3 Although low pulmonary artery pressure (PAP) is the most important criteria for successful BCPS, there are many other issues to be considered, such as pulmonary artery (PA) hypoplasia, pulmonary venous obstruction (PVO), reduced systemic ventricular function (VF), atrioventricular valve (AVV) regurgitation, and other underlying patient diseases. 4 , 5 Despite sophisticated preoperative patient selection, we encounter certain patients who demonstrated severe hypoxemia after BCPS, so called failing BCPS.…”

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confidence: 99%

Management of failing bidirectional cavopulmonary shunt: Influence of additional systemic-to-pulmonary-artery shunt with classic Glenn physiology

et al. 2022

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Impact of hypoxemia and re-interventions on clinical outcomes after bidirectional cavopulmonary shunt

Kido

Euringer

Burri

et al. 2022

European Journal of Cardio-Thoracic Surgery

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Objectives We sought to investigate the impact of early postoperative low arterial oxygen saturation on mortality and morbidity after bidirectional cavopulmonary shunt. Methods The medical records of all patients who underwent bidirectional cavopulmonary shunt between 2013 and 2018 were reviewed. Results A total of 164 patients were included in this study. Forty-seven patients underwent reintervention during hospital stay at median 7 days after bidirectional cavopulmonary shunt. Before reintervention, 30 patients were intubated or had SpO2 of less than 75%. All re-interventions for Glenn pathway obstruction and 4 out of 5 venovenous coil embolization resulted in hospital discharge, while high mortality was observed after other re-interventions (atrioventricular valve surgery, thrombolysis, systemic ventricular outflow obstruction relief, extracorporeal membrane oxygenation implantation, and diaphragmatic plication). Additional aortopulmonary shunt with pulmonary artery discontinuation was performed in 8 patients who showed severe cyanosis with median SpO2 of 59% under maximal ventilation support. In univariable Cox regression analysis, the associated factors for mortality before total cavopulmonary connection were reduced ventricular function (HR 6.89, 95% CI 1.76–26.9, P value 0.006), greater than moderate atrioventricular valve regurgitation (HR 5.89, 95% CI 1.70–20.4, P value 0.005), SpO2 1 hour after extubation (HR 0.87, 95% CI 0.80–0.96, P value 0.004), and mean pulmonary artery pressure 1 hour after extubation (HR 1.14, 95% CI 1.02–1.26, P value 0.016). Conclusions After bidirectional cavopulmonary shunt, unacceptable cyanosis persisted with various etiologies. Low arterial oxygen saturation within 1 hour after extubation is significantly associated with high mortality after bidirectional cavopulmonary shunt.

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Risk Factors for Thrombus Formation at Stage 2 Palliation and Its Effect on Long-Term Outcome in Patients With Univentricular Heart

Cited by 3 publications

References 33 publications

Computational Analysis of the Related Factors of Deep Vein Thrombosis (DVT) Formation in Patients Undergoing Hip Fracture Surgery

Computational Analysis of the Related Factors of Deep Vein Thrombosis (DVT) Formation in Patients Undergoing Hip Fracture Surgery

Management of failing bidirectional cavopulmonary shunt: Influence of additional systemic-to-pulmonary-artery shunt with classic Glenn physiology

Impact of hypoxemia and re-interventions on clinical outcomes after bidirectional cavopulmonary shunt

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