A low cost and open access system for rapid synthesis of large volumes of gold and silver nanoparticles

Abstract

Rapid synthesis of nanomaterials in scalable quantities is critical for accelerating the discovery and commercial translation of nanoscale-based technologies. The synthesis of metal nanogold and silver in volumes larger than 100 mL is not automatized and might require of the use of harsh conditions that in most cases is detrimental for the production of nanoparticles with reproducible size distributions. In this work, we present the development and optimization of an open-access low-cost NanoParticle Flow Synthesis System (NPFloSS) that allows for the rapid preparation of volumes of up to 1 L of gold and silver nanoparticle aqueous solutions.

Drug Release Profiles of Mitomycin C Encapsulated Quantum Dots–Chitosan Nanocarrier System for the Possible Treatment of Non-Muscle Invasive Bladder Cancer

“…In this study, Tween-20 acts as a stabilizing, capping agent that forms interaction with water molecules through its hydrophilic domains, and hence accelerates the interaction of NPs with the aqueous medium. It is noteworthy to mention that Tween-20 is a safe addition to biomedical NPs formulations [ 29 ].…”

Continuous-flow syntheses of alloy nanoparticles

“…24–26 The flow syntheses of metallic NPs, including monometallic and alloy NPs, are also well studied. The syntheses of monometallic Au and Ag are the most well-studied topics 27–30 and account for approximately half of the reports. However, there are fewer reports about alloy NPs than monometallic NPs.…”

First investigation of the morphological and luminescence properties of HfO2 nanoparticles synthesized by photochemical synthesis

“…[39][40][41][42][43][44] The perspective of the up scaling of the method has already been shown. 45,46 The advantage of exploiting the photochemical route for the production of large amounts of NPs comes from several evidence, among which, the softening of strict control of temperature (T) and pH parameters, required in the majority of chemical methodologies. Moreover, by choosing the stoichiometry of the precursors and reaction times, the chemical product of the synthesis can be easily doped, and its size can be scaled down to the nanometer size, a peculiarity that is mandatory for the creation of scintillating nanocomposites to avoid scattering and the subsequent reduction of transparency.…”