A concealed inguinal presentation of a gastrointestinal stromal tumor (GIST): a case report and literature review

Abstract

Background Gastrointestinal stromal tumor (GIST) can arise anyplace along the gastrointestinal (GI) tract. The uncommon tumor location in groin area is rarely reported. Case presentation We herein reported a metastasized case presented as GI hemorrhage complicated with indirect hernia, and underwent tumor cytoreduction, herniorrhaphy and chemotherapy for jejunal GIST. The case was described consecutively based on the process of surgical management, with a good follow-up result. A literature review by searching similar case reports from two national medical databases was performed to summarize clinical features of such unusual presentation of GIST, which included hernia characteristics, short- and long-term outcomes of this disease. It showed GIST presenting as groin hernia was rarely reported and all available 11 cases suggested a primary tumor and required both tumor resection and hernia repair. The long-term results indicated 64.3% overall survival at 5 years after the incidental diagnosis. Conclusions Inguinal hernia is an extremely rare presentation of GIST, with limited case reports available in the literature. A radical involving tumor resection plus hernia repair is an optimal surgical approach for such uncommon condition. An adjuvant medication mounting on mutated KIT gene should be strictly followed for high risk cases.

Ruptured Large Gastrointestinal Stromal Tumor: A Case Report and Review of Literature

“…The ruptured mass was seen on CT measuring 5.2 cm × 4.1 cm × 3.0 cm. Moreover, in this report, the patient also had a metastatic groin mass with histopathology and immunohistochemistry reports characteristic of GIST findings [ 2 ].…”

“…A gastrointestinal stromal tumor (GIST) is known to be the most common mesenchymal tumor that tends to arise anyplace in the alimentary canal, accounting for almost 60% of all gastric stromal tumors [ 1 , 2 ]. According to the National Institutes of Health guidelines, GISTs are classified per their size, location, and degree of mitoses [ 3 ].…”