An initial trial of quantitative evaluation of autoimmune pancreatitis using shear wave elastography and shear wave dispersion in transabdominal ultrasound

Suzuki, Hirotaka; Ishikawa, Takuya; Ohno, Eizaburo; Iida, Tadashi; Uetsuki, Kota; Yashika, Jun; Yamada, Kenta; Yoshikawa, Masakatsu; Nakamura, Masanao; Honda, Takashi; Ishigami, Masatoshi; Kawashima, Hiroki; Fujishiro, Mitsuhiro

doi:10.1016/j.pan.2021.02.014

Cited by 7 publications

(14 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Although it has been reported that degeneration and necrosis of cancer cells, fibrosis of the stroma, and infiltration of inflammatory cells were found in resected pathological specimens after chemotherapy, 24 SWD and SWE values would not reflect these histopathological changes in the short term. In the previous report regarding AIP, both SWD and SWE values significantly decreased after 2 weeks of steroid administration and were useful for treatment evaluation 20 . This may reflect the characteristics of AIP, which tends to show dramatic short‐term pathological improvement after steroid treatment.…”

Section: Discussionmentioning

confidence: 81%

“…In dynamics, there is a relationship between high fluidity and low viscosity, as well as low fluidity and high viscosity, which is consistent with our findings. In contrast, a study with AIP reported that both SWD and SWE values were higher than in the healthy group 20 . In clinical practice, as it is occasionally difficult to differentiate PDA from AIP, the difference in viscosity quantified by SWD values between them would be available in the diagnosis.…”

Section: Discussionmentioning

confidence: 88%

“…In the previous report regarding AIP, both SWD and SWE values significantly decreased after 2 weeks of steroid administration and were useful for treatment evaluation. 20 This may reflect the characteristics of AIP, which tends to show dramatic short-term pathological improvement after steroid treatment. Therefore, long-term changes in SWD and SWE values at PDA sites might be detectable.…”

Section: Discussionmentioning

confidence: 99%

“…There have been several reports of a shear wave dispersion slope (SWD) value in liver disease, including inflammation and necrosis, 5,13,14 steatosis, 15 fibrosis, 16,17 and benign and malignant diagnoses of tumors 18 . There have been two reports of the dispersion imaging in the pancreas: one of which indicated that SWD was associated with steatosis of pancreatic parenchyma 19 ; the other of which indicated that SWD value was high in autoimmune pancreatitis (AIP) and was associated with the effect of steroid therapy 20 . Meanwhile, there have been no reports on pancreatic cancer.…”

Section: Introductionmentioning

confidence: 99%

“…18 There have been two reports of the dispersion imaging in the pancreas: one of which indicated that SWD was associated with steatosis of pancreatic parenchyma 19 ; the other of which indicated that SWD value was high in autoimmune pancreatitis (AIP) and was associated with the effect of steroid therapy. 20 Meanwhile, there have been no reports on pancreatic cancer.…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Clinical significance of dispersion imaging by shear wave elastography in the treatment and diagnosis of pancreatic cancer

Takishin

Kuwatani

Nishida

et al. 2023

J of Gastro and Hepatol

View full text Add to dashboard Cite

Declaration of conflict of interest: NaoyaSakamoto is an Editorial Board member of JGH and a co-author of this article. To minimize bias, they were excluded from all editorial decision making related to the acceptance of this article for publication. Ethical approval: This study (registration number: UMIN000040173) was conducted in compliance with the ethical guidelines of the Declaration of Helsinki and the ethical guidelines for medical and health research

show abstract

Section: Discussionmentioning

confidence: 81%

Section: Discussionmentioning

confidence: 88%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Clinical significance of dispersion imaging by shear wave elastography in the treatment and diagnosis of pancreatic cancer

Takishin

Kuwatani

Nishida

et al. 2023

J of Gastro and Hepatol

View full text Add to dashboard Cite

show abstract

Point‐shear wave elastography generated by acoustic radiation force impulse in chronic pancreatitis

Wekerle,

Murillo,

vonBoscamp

et al. 2024

UEG Journal

View full text Add to dashboard Cite

BackgroundTranscutaneous point‐shear wave elastography (p‐SWE) performed using an acoustic radiation force impulse can be used to quantify pancreatic stiffness in chronic pancreatitis (CP). We aimed to evaluate its usefulness to diagnose and monitor CP.Methods175 participants were included in this prospective study including patients with CP (n = 65), liver cirrhosis (LC; n = 60), alcohol abuse (n = 10) and healthy controls (n = 40). Point‐shear wave elastography of the pancreas was performed and quantified as median shear wave velocity (SWV). In the same way, p‐SWE of the spleen served as a marker of portal hypertension. The M‐ANNHEIM Severity score was used as global marker for disease activity in CP.ResultsCompared to healthy controls, pancreatic SWV was significantly elevated in CP (1.38 vs. 0.96 m/s; p < 0.0001, MWU‐test). Pancreatic SWV was increased in alcoholic CP but not in hereditary CP. Receiver operating characteristic analysis revealed 1.2 m/s as the optimal cut‐off to identify non‐heredity‐CP subjects (90% specificity; 81% sensitivity; 92% positive predictive value). Pancreatic SWV correlated significantly with the M‐ANNHEIM Severity score, severity of CP‐typical complications (both p < 0.05, linear regression analysis), morphological changes of the pancreas and need for hospital treatment (both p < 0.05, MWU‐test) but not with exocrine or endocrine insufficiency. Pancreatic SWV >1.7 m/s was identified to predict M‐ANNHEIM Severity score ≥11 points. Pancreatic SWV was also elevated in LC (1.42 m/s; p < 0.001), correlating with increased splenic SWV.ConclusionTranscutaneous pancreatic p‐SWE represents a bedside, cost‐effective and non‐invasive tool which adds valuable information to the process of diagnosing and monitoring CP. By portal hypertension, an increased pancreatic SWV must be expected.

show abstract

Incidence of endocrine and exocrine insufficiency in patients with autoimmune pancreatitis at diagnosis and after treatment: a systematic review and meta-analysis

Lanzillotta

Tacelli

Falconi

et al. 2022

European Journal of Internal Medicine

View full text Add to dashboard Cite

An initial trial of quantitative evaluation of autoimmune pancreatitis using shear wave elastography and shear wave dispersion in transabdominal ultrasound

Cited by 7 publications

References 30 publications

Clinical significance of dispersion imaging by shear wave elastography in the treatment and diagnosis of pancreatic cancer

Clinical significance of dispersion imaging by shear wave elastography in the treatment and diagnosis of pancreatic cancer

Point‐shear wave elastography generated by acoustic radiation force impulse in chronic pancreatitis

Incidence of endocrine and exocrine insufficiency in patients with autoimmune pancreatitis at diagnosis and after treatment: a systematic review and meta-analysis

Contact Info

Product

Resources

About