Abstract:Autophagy is a lysosomal-dependent degradation pathway in eukaryotic cells. Recent
studies have reported that autophagy can facilitate the activation of hepatic stellate
cells (HSCs) and fibrogenesis of the liver during long-term carbon tetrachloride
(CCl
4
) exposure. However, little is known about the role of autophagy in
CCl
4
-induced acute hepatic failure (AHF). This study aimed to identify
whether modulation of autophagy can affect CCl
4
… Show more
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