Duration of effect of Biotène spray in patients with symptomatic dry mouth: A pilot study

Lung, Christine Bambi; Watson, Gene E.; Verma, Swati; Feng, Changyong; Saunders, Ralph H.

doi:10.1016/j.oooo.2020.12.002

Cited by 6 publications

(5 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Cleaning the oral mucosa and applying oral moisturizers are effective methods for avoiding dry mouth and preventing the formation of membranous substances [ 9 , 39 , 40 ]. However, as the effect of moisturizers is short-lasting [ [41] , [42] , [43] ], membranous substances begin to re-form and stick strongly to the oral mucosa 12–24 h after oral care [ 40 ]. Therefore, it is important to perform oral care at 6–12 h intervals [ 40 ] as it would be easier to remove these membranous substances before they become firmly attached to the oral mucosa.…”

Section: Discussionmentioning

confidence: 99%

Palatal microbiota associated with membranous substances in older Japanese individuals undergoing tube feeding in long-term care: A cross-sectional study

Asahina,

Ogasawara,

Akieda

et al. 2023

Heliyon

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Palatal microbiota associated with membranous substances in older Japanese individuals undergoing tube feeding in long-term care: A cross-sectional study

Asahina,

Ogasawara,

Akieda

et al. 2023

Heliyon

View full text Add to dashboard Cite

“…Treatment of dry mouth alleviates symptoms by improving salivary secretion. Various management strategies include increased hydration (approximately 2 L of water daily), use of humidifiers, mechanical salivary/gustatory stimulants (such as sugar-free candy or chewing gum), medications, and saliva substitutes/oral moisturizers . A 2011 Cochrane meta-analysis of 36 RCTs involving 1597 patients assessed various topical interventions for dry mouth relief .…”

Section: Methodsmentioning

confidence: 99%

“…Various management strategies include increased hydration (approximately 2 L of water daily), use of humidifiers, mechanical salivary/gustatory stimulants (such as sugar-free candy or chewing gum), medications, and saliva substitutes/oral moisturizers. [18][19][20][21][22] A 2011 Cochrane meta-analysis of 36 RCTs involving 1597 patients assessed various topical interventions for dry mouth relief. 23 Results reported that oxygenated glycerol triester spray was more effective in relieving mouth dryness compared with an electrolyte spray (standardized mean difference, 0.77 [95% CI, 0.38 to 1.15]), which corresponds with a mean difference of approximately 2 points on a 10-point visual analog scale for dry mouth (0 [no dry mouth] to 10 [most severe mouth dryness]) (considered clinically significant).…”

Section: Treatmentmentioning

confidence: 99%

Common Oral Conditions

Stoopler,

Villa,

Bindakhil

et al. 2024

JAMA

View full text Add to dashboard Cite

ImportanceDry mouth, oral candidiasis, and recurrent aphthous ulcers are 3 of the most common oral conditions that may be associated with patient discomfort, decreased quality of life, and morbidity.ObservationsIn a meta-analysis of 26 population-based cohort and cross-sectional studies, the global prevalence of dry mouth symptoms was 23% (95% CI, 18% to 28%), placing individuals at risk of oral candidiasis, dental caries, dysgeusia, masticatory/speech impairment, and oropharyngeal dysphagia. Dry mouth is associated with using more than 3 oral medications per day (odds ratio [OR], 2.9 [95% CI, 1.4 to 6.2]), head and neck radiation, and Sjögren disease. Symptoms may include difficulty swallowing and speaking, thirst, and halitosis. Dry mouth is associated with an 11.5% (95% CI, 3.6% to 27%) higher risk of oral candidiasis, based on a meta-analysis of 6 observational cohorts. Management of dry mouth includes mechanical salivary stimulants, oral moisturizers, and/or systemic sialagogues. Oral candidiasis is an opportunistic fungal infection caused by overgrowth of the Candida genus with C albicans, which accounts for 76.8% of infections. The prevalence of oral candidiasis is higher in patients who are immunosuppressed, for example, those with HIV (35% [95% CI, 28% to 42%]) and those with salivary gland hypofunction (OR, 3.02 [95% CI, 1.73 to 5.28]). Common risk factors associated with oral candidiasis include use of antibiotics (P = .04) and oral mucosal disorders such as lichen planus. Oral burning and dysgeusia are common symptoms of oral candidiasis. Treatment includes addressing risk factors and use of topical and/or systemic antifungal medications. Recurrent aphthous stomatitis is characterized by symptomatic round or oval oral ulcers, which are covered by a gray-white fibrin layer and encircled by an erythematous ring. A meta-analysis of 10 case-controlled studies revealed an increased risk of recurrent aphthous stomatitis associated with polymorphism of IL-1β (+3954C/T) (OR, 1.52 [95% CI, 1.07 to 2.17]) and IL-1β (−511C/T) (OR, 1.35 [95% CI, 1.09 to 1.67]). Another meta-analysis of 9 case-control studies reported that patients with recurrent aphthous stomatitis had a higher frequency of nutritional deficiencies, including vitamin B12 (OR, 3.75 [95% CI, 2.38 to 5.94]), folic acid (OR, 7.55 [95% CI, 3.91 to 14.60]), and ferritin (OR, 2.62 [95% CI, 1.69 to 4.06]). Recurrent aphthous stomatitis can be associated with systemic diseases. A meta-analysis of 21 case-control studies revealed that celiac disease is associated with a higher incidence of recurrent aphthous stomatitis (25% vs 11%; OR, 3.79 [95% CI, 2.67 to 5.39]; P &lt;.001). Topical corticosteroids are first-line agents to manage recurrent aphthous stomatitis; however, systemic medications may be necessary in more severe cases.Conclusions and RelevanceDry mouth, oral candidiasis, and recurrent aphthous ulcers are common oral conditions that may be associated with patient discomfort, decreased quality of life, and morbidity. First-line treatment includes over-the-counter sialagogues for dry mouth, topical antifungals for oral candidiasis, and topical corticosteroids for aphthous ulcers. Oral conditions that do not improve with first-line treatment may require treatment with systemic medications.

show abstract

“…Saliva replacements and other dry mouth products [25] may potentially affect the corrosion of dental alloys. These products may relieve the symptoms of xerostomia [1] for a short period of time [25][26][27], so the patients have to use them many times a day. However, the effect of dry mouth products on the corrosion of dental alloys is poorly investigated.…”

Section: Introductionmentioning

confidence: 99%

The Impact of Commercially Available Dry Mouth Products on the Corrosion Resistance of Common Dental Alloys

et al. 2023

View full text Add to dashboard Cite

Dental implants are thought to be implanted for life, but throughout their lifespan, they function in aggressive oral environment, resulting in corrosion of the material itself as well as possible inflammation of adjacent tissues. Therefore, materials and oral products for people with metallic intraoral appliances must be chosen carefully. The purpose of this study was to investigate the corrosion behavior of common titanium and cobalt–chromium alloys in interaction with various dry mouth products using electrochemical impedance spectroscopy (EIS). The study showed that different dry mouth products lead to different open circuit potentials, corrosion voltages, and currents. The corrosion potentials of Ti64 and CoCr ranged from −0.3 to 0 V and −0.67 to 0.7 V, respectively. In contrast to titanium, pitting corrosion was observed for the cobalt–chromium alloy, leading to the release of Co and Cr ions. Based on the results, it can be argued that the commercially available dry mouth remedies are more favorable for dental alloys in terms of corrosion compared to Fusayama Meyer’s artificial saliva. Thus, to prevent undesirable interactions, the individual characteristics of not only the composition of each patient’s tooth and jaw structure, but also the materials already used in their oral cavity and oral hygiene products, must be taken into account.

show abstract

Duration of effect of Biotène spray in patients with symptomatic dry mouth: A pilot study

Cited by 6 publications

References 15 publications

Palatal microbiota associated with membranous substances in older Japanese individuals undergoing tube feeding in long-term care: A cross-sectional study

Palatal microbiota associated with membranous substances in older Japanese individuals undergoing tube feeding in long-term care: A cross-sectional study

Common Oral Conditions

The Impact of Commercially Available Dry Mouth Products on the Corrosion Resistance of Common Dental Alloys

Contact Info

Product

Resources

About