Macroscopic T-wave alternans in a patient presenting with hepatic encephalopathy

Macroscopic T Wave Alternans --Unusual Presentation in Cirrhotic Patients.

“…In cirrhotic patients, the precise mechanism of QT prolongation is not well understood. However, it is believed to be related to cardiac ion channel remodeling, autonomic dysfunction, and impaired drug metabolism (5). Studies have shown that around 60% of advanced cirrhotic patients exhibit QTc prolongation, regardless of the underlying cause of cirrhosis, and this prolongation is closely correlated with the severity of cirrhosis (6).…”