Early life factors and COVID-19 infection in England: A prospective analysis of UK Biobank participants

Abstract

This study aims to examine whether maternal smoking, birth weight, birth month and breastfeeding are associated with COVID-19 infection and hospitalisation. Maternal smoking was positively associated with COVID-19 infection. Breastfeeding was negatively associated with COVID-19 infection. The odds of being hospitalised due to COVID-19 were higher among those who had lower birthweight and mothers who were smoking during pregnancy.

The association of smoking status with SARS-CoV-2 infection, hospitalisation and mortality from COVID-19: A living rapid evidence review with Bayesian meta-analyses (version 11)

“…Of these self-referrals, healthcare professionals decided that current compared with former or never smokers were less likely to require a test (RR = 0.93, 95% CI = 0.86-1.0, p = 0.045). In a further study using the UK Biobank cohort (Didikoglu et al, 2021), current (RR = 1.23, 95% CI = 1.19-1.26, p < 0.001) and former smokers (RR = 1.20, 95% CI = 1.18-1.23, p < 0.001) were more likely to receive a test compared with never smokers.…”

Balancing restrictions and access to maternity care for women and birthing partners during the COVID‐19 pandemic: the psychosocial impact of suboptimal care

“…Evidence is growing that maternal perinatal stress has thus long‐term impacts on aspects of child development and health. The importance of this perinatal period for the lifelong health of the infant has been highlighted in a recent retrospective study: 13 adults aged between 47 and 83 that were breastfed as children had a 12% lower chance of contracting COVID, whereas those exposed to maternal smoking around birth had a 20% higher risk of infection and 24% higher risk of hospitalisation due to COVID‐19 after adjustment for later‐life socio‐economic and environmental factors 14 …”

“…The importance of this perinatal period for the lifelong health of the infant has been highlighted in a recent retrospective study: 13 adults aged between 47 and 83 that were breastfed as children had a 12% lower chance of contracting COVID, whereas those exposed to maternal smoking around birth had a 20% higher risk of infection and 24% higher risk of hospitalisation due to COVID-19 after adjustment for later-life socio-economic and environmental factors. 14 Extrapolation of these data to the current maternity care situation suggests that the actions taken to reduce risks due to COVID-19 may negatively impact maternal psychosocial functioning, early parenting and, consequently, child developmental outcomes. It is thus important to document these deviations from best practice, and to reverse them as soon as possible.…”

Aleitamento materno e Covid-19: revisão sistemática e recomendações baseada em evidências / Breastfeeding and Covid-19: systematic review and recommendations based on evidence

“…Didikoglu et al 15 Pereira et al 18 (2020) realizou um estudo com uma série de 22 casos de recémnascidos cujas mães apresentaram infecção por CV-19. Tanto mães quanto recémnascidos foram acompanhados por um período médio de 1,8 meses consecutivos, correspondendo a 20 mães (90,9%) as que optaram por amamentar os lactentes durante a internação e o contato pele a pele na sala de parto foi realizado em 59,1%, sendo que 88% dos recém-nascidos de mães com CV-19 foram alimentados com leite materno após 1 mês, diminuindo para 77% aos 1,8 meses, sugerindo que o AME em recém-nascidos de mães com CV-19 é seguro se medidas de controle de infecção adequadas forem tomadas.…”