Herbal Supplements for Common Women’s Health Issues

Morehead, Angela; McInnis, Leigh Ann

doi:10.1016/j.cnur.2020.10.006

Cited by 5 publications

(2 citation statements)

References 17 publications

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“…Most phytomedicines are available without prescription. In general, safety data for use during pregnancy are lacking for phytomedicines (Bernstein et al, 2021;Morehead and McInnis, 2021). For example, it is not known whether pharmacologically active compounds in these products can cross the placental barrier.…”

Section: Introductionmentioning

confidence: 99%

Transplacental passage of hyperforin, hypericin, and valerenic acid

et al. 2023

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Safe medications for mild mental diseases in pregnancy are needed. Phytomedicines from St. John’s wort and valerian are valid candidates, but safety data in pregnancy are lacking. The transplacental transport of hyperforin and hypericin (from St. John’s wort), and valerenic acid (from valerian) was evaluated using the ex vivo cotyledon perfusion model (4 h perfusions, term placentae) and, in part, the in vitro Transwell assay with BeWo b30 cells. Antipyrine was used for comparison in both models. U(H)PLC-MS/MS bioanalytical methods were developed to quantify the compounds. Perfusion data obtained with term placentae showed that only minor amounts of hyperforin passed into the fetal circuit, while hypericin did not cross the placental barrier and valerenic acid equilibrated between the maternal and fetal compartments. None of the investigated compounds affected metabolic, functional, and histopathological parameters of the placenta during the perfusion experiments. Data from the Transwell model suggested that valerenic acid does not cross the placental cell layer. Taken together, our data suggest that throughout the pregnancy the potential fetal exposure to hypericin and hyperforin – but not to valerenic acid – is likely to be minimal.

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Section: Introductionmentioning

confidence: 99%

Transplacental passage of hyperforin, hypericin, and valerenic acid

et al. 2023

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“…Herbal medicine has been widely used by women globally and increasingly more have shown the necessity of herbal medicines, both in treating diseases and maintaining health (Homaie Rad et al, 2021;Morehead and McInnis, 2021). Even in the modern world, there continue to be several health issues among women that cannot be cured using modern medicine; and in some regions having no modern medicines, it continues to be necessary to use herbal medicine as an alternative or supplement for women's health and facilitate their life (Peltzer, 2009).…”

Section: Introductionmentioning

confidence: 99%

Comparison of Herbal Medicines Used for Women’s Menstruation Diseases in Different Areas of the World

et al. 2022

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Aims: This review aims to compare the use of herbal medicine used to treat women’s menstruation and the prevalence of menstrual diseases in different regions, which reveal the use of herbal medicine globally and provide scientific guidance for improving women’s health.Materials and Methods: The information available on herbal medicines for women between the years 2000 and 2021 was systematically collected via the library and electronic search systems such as Google Scholar, PubMed, ScienceDirect, and Web of Science as well as secondary resources including books and conference proceedings.Results: Totally, 571 ethnic medicines commonly used for women’s menstruation health in Asia, Europe, Oceania, Africa, and America were accounted. Zingiber officinale Roscoe (Ginger), Ruta graveolens L. (Common rue), Angelica sinensis (Oliv.) Diels (Angelica sinensis), Foeniculum vulgare Mill (Fennel), Catharanthus roseus (L.) G. Don (Catharanthus roseus) and other medicines which have obvious advantages and long-term usage are utilized in the treatment of menstrual diseases. Family Asteraceae, Lamiaceae, Apiaceae, Fabaceae, and Zingiberaceae are the most common medicinal plant families used for such treatments. In many instances, the application of fresh parts of plants was observed because of the healers’ belief regarding the higher efficiency of the medicine made from fresh plants. Edible plants are used in a wide range of countries.Conclusion: Women’s menstruation health is directly related to their health condition. Traditional medicines of most ethnic groups have contributed to women’s health care and treatment of gynecological diseases. Practitioners in this field have gained elaborate experience in treatments and medication, and assembled a large number of effective drugs and prescriptions. These experiences have also been inherited and developed by modern clinical application and scientific research. However, the basic research on these drugs is not sufficient, the knowledge of drug use has not been fully popularized, the advantages of drugs have not been fully utilized, and the guiding potential to modern drug research continues to be insufficient. As such, it is necessary to further promote and make a significant contribution to women’s health.

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