The tertiary oxime monoisonitrosoacetone penetrates the brain, reactivates inhibited acetylcholinesterase, and reduces mortality and morbidity following lethal sarin intoxication in guinea pigs

Shih, Tsung‐Ming; Oyler, Benjamin L.; Capacio, Benedict R.; Koplovitz, Irwin

doi:10.1016/j.taap.2021.115443

Toxicology and Applied Pharmacology

2021

DOI: 10.1016/j.taap.2021.115443

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The tertiary oxime monoisonitrosoacetone penetrates the brain, reactivates inhibited acetylcholinesterase, and reduces mortality and morbidity following lethal sarin intoxication in guinea pigs

Tsung‐Ming Shih¹,

Benjamin L. Oyler²,

Benedict R. Capacio³

et al.

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The risk associated with organophosphorus nerve agents: from their discovery to their unavoidable threat, current medical countermeasures and perspectives

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The tertiary oxime monoisonitrosoacetone penetrates the brain, reactivates inhibited acetylcholinesterase, and reduces mortality and morbidity following lethal sarin intoxication in guinea pigs

Cited by 1 publication

References 10 publications

The risk associated with organophosphorus nerve agents: from their discovery to their unavoidable threat, current medical countermeasures and perspectives

The risk associated with organophosphorus nerve agents: from their discovery to their unavoidable threat, current medical countermeasures and perspectives

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