Abstract:OBJECTIVES
Patients with bicuspid aortic valve (BAV) comprise a substantial portion of patients undergoing surgical aortic valve replacement (SAVR). Our goal was to quantify the prevalence of BAV in the current SAVR ± coronary artery bypass grafting (CABG) population, assess differences in cardiovascular risk profiles and assess differences in long-term survival in patients with BAV compared to patients with tricuspid aortic valve (TAV).
METHO… Show more
“…Nine studies 12 13 17 18 19 20 21 22 23 reported on the prevalence of prior myocardial infarction, which included a total of 6,504 patients. Myocardial infarction was reported in 768 (11.8%) of the total group.…”
Section: Coronary Artery Diseasementioning
confidence: 99%
“…Six studies 12 13 18 19 21 24 reported on the prevalence of a prior PCI, which included a total of 43,413 patients. A PCI was performed in the past in a total of 2,051 (4.7%) patients.…”
Section: Coronary Artery Diseasementioning
confidence: 99%
“…Twenty-five studies 7 12 13 18 20 23 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 reported on the prevalence of a concomitant CABG, which included a total of 16,095 patients. A concomitant CABG was performed in a total of 5,581 (34.7%) patients.…”
Section: Coronary Artery Diseasementioning
confidence: 99%
“…Thirty-five studies 7 12 13 17 18 19 20 21 22 23 24 25 26 28 29 32 33 34 36 39 40 45 46 47 48 49 50 51 52 53 54 55 56 57 58 reported on the prevalence of hypertension, which included 52,807 patients. Hypertension was present in a total of 34,892 (66.1%) patients.…”
The prevalence of coronary artery disease (CAD) in bicuspid aortic valve (BAV) patients is a debatable topic. Several studies have indicated that BAV patients have a lower prevalence of CAD compared with patients with a tricuspid aortic valve (TAV), but the effects of age and gender have not always been considered. This systematic review provides an overview of articles which report on CAD in BAV and TAV patients. Searches were executed in April 2021 and January 2022 according to the PRISMA (Preferred Reporting Items for Systematic reviews and Meta-analyses) guidelines in three online databases: Medline, Embase, and Scopus. Screening and data extraction was done by two investigators separately. Primary and secondary outcomes were compared between BAV and TAV patients; a fixed effects model was used for correcting on confounders. Literature search yielded 1,529 articles with 44 being eligible for inclusion. BAV patients were younger (56.4 ± 8.3 years) than TAV patients (64 ± 10.3 years, p < 0.001). All CAD risk factors and CAD were more prevalent in TAV patients. No significant difference remained after correcting for age and gender as confounders. BAV patients have a lower prevalence of CAD and CAD risk factors compared with TAV patients. However, when the age differences between both groups are considered in the analyses, a similar prevalence of both CAD and CAD risk factors is found.
“…Nine studies 12 13 17 18 19 20 21 22 23 reported on the prevalence of prior myocardial infarction, which included a total of 6,504 patients. Myocardial infarction was reported in 768 (11.8%) of the total group.…”
Section: Coronary Artery Diseasementioning
confidence: 99%
“…Six studies 12 13 18 19 21 24 reported on the prevalence of a prior PCI, which included a total of 43,413 patients. A PCI was performed in the past in a total of 2,051 (4.7%) patients.…”
Section: Coronary Artery Diseasementioning
confidence: 99%
“…Twenty-five studies 7 12 13 18 20 23 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 reported on the prevalence of a concomitant CABG, which included a total of 16,095 patients. A concomitant CABG was performed in a total of 5,581 (34.7%) patients.…”
Section: Coronary Artery Diseasementioning
confidence: 99%
“…Thirty-five studies 7 12 13 17 18 19 20 21 22 23 24 25 26 28 29 32 33 34 36 39 40 45 46 47 48 49 50 51 52 53 54 55 56 57 58 reported on the prevalence of hypertension, which included 52,807 patients. Hypertension was present in a total of 34,892 (66.1%) patients.…”
The prevalence of coronary artery disease (CAD) in bicuspid aortic valve (BAV) patients is a debatable topic. Several studies have indicated that BAV patients have a lower prevalence of CAD compared with patients with a tricuspid aortic valve (TAV), but the effects of age and gender have not always been considered. This systematic review provides an overview of articles which report on CAD in BAV and TAV patients. Searches were executed in April 2021 and January 2022 according to the PRISMA (Preferred Reporting Items for Systematic reviews and Meta-analyses) guidelines in three online databases: Medline, Embase, and Scopus. Screening and data extraction was done by two investigators separately. Primary and secondary outcomes were compared between BAV and TAV patients; a fixed effects model was used for correcting on confounders. Literature search yielded 1,529 articles with 44 being eligible for inclusion. BAV patients were younger (56.4 ± 8.3 years) than TAV patients (64 ± 10.3 years, p < 0.001). All CAD risk factors and CAD were more prevalent in TAV patients. No significant difference remained after correcting for age and gender as confounders. BAV patients have a lower prevalence of CAD and CAD risk factors compared with TAV patients. However, when the age differences between both groups are considered in the analyses, a similar prevalence of both CAD and CAD risk factors is found.
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