Association of Participation in Health Check-ups with Risk Factors for Cardiovascular Diseases

Park, Bok Hyun; Lee, Byung Kook; Ahn, Jaeouk; Kim, Nam Soo; Park, Jungsun; Kim, Yangho

doi:10.3346/jkms.2021.36.e19

Cited by 11 publications

(11 citation statements)

References 22 publications

(34 reference statements)

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“…A review article also reported that general health checks were associated with increased detection and treatment of chronic diseases, but had little impact on mortality or cardiovascular event reductions [ 31 ]. However, these results remain controversial as other studies have reported that health check participation is associated with fewer cardiovascular risk factors [ 13 ], risk factor value reductions [ 32 ], and mortality reductions [ 33 ]. Additional studies have been conducted to identify social elements that can affect participation, such as perceived susceptibility and health knowledge [ 34 , 35 ], socioeconomic status [ 36 , 37 ], medical history [ 38 , 39 , 40 , 41 ], health behavior factors, and sociodemographic factors [ 42 , 43 ].…”

Section: Discussionmentioning

confidence: 99%

“…Several studies have examined the relationship between health check-up participation and cardiovascular risk factors [ 13 , 14 , 15 ], finding that receiving health test interventions are associated with lowered risk scores and better life expectancy [ 15 ], lower risks of all-cause mortality and cardiovascular events [ 14 ], and lower prevalence of several diseases, including metabolic syndrome [ 13 ], and that screening interval can affect health outcomes [ 16 , 17 ]. Meanwhile, however, some studies have indicated that screening participation has no effect on changes in disease prevalence in comparison to only receiving usual care [ 18 ].…”

Section: Introductionmentioning

confidence: 99%

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Prediction Model for Hypertension and Diabetes Mellitus Using Korean Public Health Examination Data (2002–2017)

et al. 2022

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Hypertension and diabetes mellitus are major chronic diseases that are important factors in the management of cardiovascular disease. In order to prevent the occurrence of chronic diseases, proper health management through periodic health check-ups is necessary. The purpose of this study is to determine the incidence of hypertension and diabetes mellitus according to the health check-up, and to develop a predictive model for hypertension and diabetes according to the health check-up. We used the National Health Insurance Corporation database of Korea and checked whether hypertension or diabetes occurred from that date according to the number of health check-ups over the past 10 years. Compared to those who underwent five health check-ups, those who participated in the first screening had hypertension (OR = 2.18, 95% CI = 2.14–2.22), diabetes mellitus (OR = 1.33, 95% CI = 1.30–1.35) and both diseases (OR = 2.46, 95% CI = 2.39–2.53); individuals who underwent 10 screenings had hypertension (OR = 0.86, 95% CI = 0.83–0.88), diabetes mellitus (OR = 0.83, 95% CI = 0.81–0.85) and both diseases (OR = 0.83, 95% CI = 0.79–0.87). Individuals who attended fewer than five screenings compared with individuals who attended five or more screenings had hypertension (OR = 1.61, 95% CI = 1.59–1.62; AUC = 0.66), diabetes mellitus (OR = 1.21, 95% CI =1.20–1.22; AUC = 0.59) and both diseases (OR =1.75, 95% CI = 1.72–1.78, AUC = 0.63). The machine learning-based prediction model using XGBoost showed higher performance in all datasets than the conventional logistic regression model in predicting hypertension (accuracy, 0.828 vs. 0.628; F1-score, 0.800 vs. 0.633; AUC, 828 vs. 0.630), diabetes mellitus (accuracy, 0.707 vs. 0.575; F1-score, 0.663 vs. 0.576; AUC, 0.710 vs. 0.575) and both diseases (accuracy, 0.950 vs. 0.612; F1-score, 0.950 vs. 0.614; AUC, 0.952 vs. 0.612). It was found that health check-up had a great influence on the occurrence of hypertension and diabetes, and screening frequency was more important than other factors in the variable importances.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Prediction Model for Hypertension and Diabetes Mellitus Using Korean Public Health Examination Data (2002–2017)

et al. 2022

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“…Additionally, it has been found that the general health check-up rate is higher in small and medium-sized cities and large cities compared with that of rural areas. 48 Because individuals who participate in regular health checkups have fewer risk factors for cardiovascular diseases than those who do not, 49 these characteristics are considered to be associated with regional health disparities. In addition, health disparities depending on residential area are caused by differences in social structural factors that are difficult to overcome at the individual level, and among them, accessibility to health care facilities needs to be considered.…”

Section: Discussionmentioning

confidence: 99%

Measuring the Burden of Disease in Korea Using Disability-Adjusted Life Years (2008–2020)

Jung,

Kim,

Ock

et al. 2024

J Korean Med Sci

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Background The measurement of health levels and monitoring of characteristics and trends among populations and subgroups are essential for informing evidence-based policy decisions. This study aimed to examine the burden of disease in Korea for both the total population and subgroups in 2020, as well as analyze changes in disease burden from 2008 to 2020. Methods We employed the methodology developed in the Korean National Burden of Disease and Injuries Study to calculate disability-adjusted life years (DALYs) by sex, causes, region, and income level from 2008 to 2020. DALYs were derived by combining years of life lost and years lived with disability. Results In 2020, the burden of disease for the Korean population was estimated to be 25,439 DALYs per 100,000 population, reflecting a 13.8% increase since 2008. The leading causes of DALYs were diabetes mellitus, followed by low back pain and ischemic stroke. A sex-specific gap reversal was observed, with the disease burden for men surpassing that of women starting in 2017. Furthermore, variations in disease burden were identified across 250 regions and income quintiles. Conclusion It is imperative to establish appropriate health policies that prioritize the diseases with significantly increasing burdens and subgroups experiencing high disease burdens. The findings of this study are expected to serve as a foundation for developing healthcare policies aimed at improving the health levels of Koreans and achieving health equity.

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“… 23 Our findings that women experience a remarkable increase in lipid levels before they reach menopause suggests the importance of strategies to increase the participation rate of the services in women aged under 50, which can help reduce the risk of CVDs in women. 24 Likewise, interventions to prevent dyslipidemia targeting young premenopausal women should be developed and implemented prior to MT although the prevalence of dyslipidemia in women aged under 50 was much lower than that in women aged over 50.…”

Section: Discussionmentioning

confidence: 99%

Substantial Lipid Increases During Menopausal Transition in Korean Middle-Aged Women

2023

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Background Adverse lipid profiles are observed in postmenopausal women. However, there is insufficient evidence of the association between lipids and reproductive aging in Korean women. We aimed to characterize lipid changes with respect to timing relative to menopause in Korean middle-aged women. Methods This study included 1,436 premenopausal women who had a natural menopause during the follow-up period (median = 15.76 years) from the Korean Genome and Epidemiology Study (KoGES) Ansan and Anseong cohort. Lipid levels were measured every 2 years, and the magnitudes of annual lipid changes and differences in the changes by premenopausal body mass index were estimated using piecewise linear mixed-effects models. Results All lipid levels increased greatly from 3 or 5 years before menopause to 1 year after menopause in all women, regardless of their premenopausal body mass index. During the period, high-density lipoprotein cholesterol (HDL-C) levels increased at 0.42 mg/dL per year (95% confidence interval [CI], 0.29 to 0.55 mg/dL). Nevertheless, non-HDL-C levels simultaneously increased at 3.42 mg/dL per year (95% CI, 3.11 to 3.72 mg/dL), and an annual change in the non-HDL-C to HDL-C ratio was 0.05 (95% CI, 0.04 to 0.06). One year after menopause, changes in all lipid parameters significantly slowed down, except for the non-HDL-C to HDL-C ratio ( P < 0.001 for all). The ratio continued to increase until 3 years after menopause, but thereafter, the change leveled off. Conclusion Women experienced remarkable increases in lipid levels during menopausal transition, highlighting the need for early intervention strategies for cardiovascular disease prevention in women.

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Association of Participation in Health Check-ups with Risk Factors for Cardiovascular Diseases

Cited by 11 publications

References 22 publications

Prediction Model for Hypertension and Diabetes Mellitus Using Korean Public Health Examination Data (2002–2017)

Prediction Model for Hypertension and Diabetes Mellitus Using Korean Public Health Examination Data (2002–2017)

Measuring the Burden of Disease in Korea Using Disability-Adjusted Life Years (2008–2020)

Substantial Lipid Increases During Menopausal Transition in Korean Middle-Aged Women

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