Imaging in head and neck cancers

Batuwitage, Bisanth; Hanlon, Rebecca; Charters, Pia

doi:10.1016/j.bjae.2020.08.006

Cited by 3 publications

(6 citation statements)

References 8 publications

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“…However, CT is still extremely valuable for patients in whom MRI is contraindicated, to provide bony detail and when rapid scan acquisition is required. 39 A variety of techniques can be used with CT to improve visualisation in certain subsites, including: shallow free breathing for laryngeal lesions; e-phonation for lesions of the laryngeal ventricle, anterior commissure and aryepiglottic folds; and the 'puffed cheek' technique for buccal mucosa lesions. Slice thickness depends upon scanning capability, but, in general, sections are acquired at 0.625-1.25 mm and reformatted no greater than 2.5 mm for viewing.…”

Section: Computed Tomographymentioning

confidence: 99%

“…Traditionally, a scan delay of 50-75 seconds was used to allow adequate enhancement of primary tumour and accurate differentiation of cervical lymph nodes from vessels, although a delay of 90 seconds is thought to improve this further and is now used widely. 40 • No radiation • The risks of intravenous gadolinium-based contrast are also lower than with iodinated CT-based contrast 39 Limitations:…”

Section: Computed Tomographymentioning

confidence: 99%

“…However, CT is still extremely valuable for patients in whom MRI is contraindicated, to provide bony detail and when rapid scan acquisition is required. 39…”

Section: Imaging In Head and Neck Cancermentioning

confidence: 99%

“…Advantages: Superior contrast resolution No radiation The risks of intravenous gadolinium-based contrast are also lower than with iodinated CT-based contrast 39 …”

Section: Imaging In Head and Neck Cancermentioning

confidence: 99%

“…The risks of intravenous gadolinium-based contrast are also lower than with iodinated CT-based contrast 39…”

Section: Imaging In Head and Neck Cancermentioning

confidence: 99%

See 4 more Smart Citations

Head and Neck Cancer: United Kingdom National Multidisciplinary Guidelines, Sixth Edition

Homer,

Winter,

Abbey

et al. 2024

J. Laryngol. Otol.

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Section: Computed Tomographymentioning

confidence: 99%

Section: Computed Tomographymentioning

confidence: 99%

“…However, CT is still extremely valuable for patients in whom MRI is contraindicated, to provide bony detail and when rapid scan acquisition is required. 39…”

Section: Imaging In Head and Neck Cancermentioning

confidence: 99%

“…Advantages: Superior contrast resolution No radiation The risks of intravenous gadolinium-based contrast are also lower than with iodinated CT-based contrast 39 …”

Section: Imaging In Head and Neck Cancermentioning

confidence: 99%

“…The risks of intravenous gadolinium-based contrast are also lower than with iodinated CT-based contrast 39…”

Section: Imaging In Head and Neck Cancermentioning

confidence: 99%

See 3 more Smart Citations

Head and Neck Cancer: United Kingdom National Multidisciplinary Guidelines, Sixth Edition

Homer,

Winter,

Abbey

et al. 2024

J. Laryngol. Otol.

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Radiologic findings of occult nodal metastasis during clinically‐N0 salvage total laryngectomy

Chan,

Wicks,

Sethi

et al. 2024

Head & Neck

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IntroductionOccult nodal disease (OND) during clinically‐N0 salvage total laryngectomy (TL) can be detected with the Neck‐Imaging‐Reporting‐and‐Data‐Systems (NI‐RADS). However, some patients will still have OND revealed on final pathology.MethodsA retrospective study on all patients who had OND during salvage TL with elective neck dissection (END) between 2009 and 2021 was performed. Repeat CT and PET scan interpretation was performed to evaluate their preoperative imaging for suspicious features.ResultsAmong 81 salvage TL patients undergoing END, 12 (16%) had OND and a total of 26 occult nodes were identified. On pathology, the average node length [SD] was 0.6 cm [0.3]. On CT, 31% (8 of 26) had rounded morphology. On PET, most had SUVmax below blood pool. One patient scored NI‐RADS 2; the rest scored 1.ConclusionsOn re‐review of preoperative imaging, occult nodes were subtle and challenging to identify. Despite no clear impact on survival, performing an END may provide prognostic information.

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Mapping the Potential of Microfluidics in Early Diagnosis and Personalized Treatment of Head and Neck Cancers

Pillai,

Kwan,

Yaziji

et al. 2023

Cancers

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Head and neck cancers (HNCs) account for ~4% of all cancers in North America and encompass cancers affecting the oral cavity, pharynx, larynx, sinuses, nasal cavity, and salivary glands. The anatomical complexity of the head and neck region, characterized by highly perfused and innervated structures, presents challenges in the early diagnosis and treatment of these cancers. The utilization of sub-microliter volumes and the unique phenomenon associated with microscale fluid dynamics have facilitated the development of microfluidic platforms for studying complex biological systems. The advent of on-chip microfluidics has significantly impacted the diagnosis and treatment strategies of HNC. Sensor-based microfluidics and point-of-care devices have improved the detection and monitoring of cancer biomarkers using biological specimens like saliva, urine, blood, and serum. Additionally, tumor-on-a-chip platforms have allowed the creation of patient-specific cancer models on a chip, enabling the development of personalized treatments through high-throughput screening of drugs. In this review, we first focus on how microfluidics enable the development of an enhanced, functional drug screening process for targeted treatment in HNCs. We then discuss current advances in microfluidic platforms for biomarker sensing and early detection, followed by on-chip modeling of HNC to evaluate treatment response. Finally, we address the practical challenges that hinder the clinical translation of these microfluidic advances.

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Imaging in head and neck cancers

Cited by 3 publications

References 8 publications

Head and Neck Cancer: United Kingdom National Multidisciplinary Guidelines, Sixth Edition

Head and Neck Cancer: United Kingdom National Multidisciplinary Guidelines, Sixth Edition

Radiologic findings of occult nodal metastasis during clinically‐N0 salvage total laryngectomy

Mapping the Potential of Microfluidics in Early Diagnosis and Personalized Treatment of Head and Neck Cancers

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