Associations Between Early Structural Magnetic Resonance Imaging, Hammersmith Infant Neurological Examination, and General Movements Assessment in Infants Born Very Preterm

Diffuse white matter abnormality in very preterm infants at term reflects reduced brain network efficiency

“…We used the standardized scoring system developed by Kidokoro et al, 2013 , Harpster, 2021 to derive a brain abnormality score for each study subject. The overall score is the sum of four individual scores quantifying the extent of abnormalities in 1) the cortical grey matter, 2) the cerebral white matter, 3) the deep grey matter, and 4) the cerebellum.…”

Hammersmith Infant Neurological Examination in low‐risk infants born very preterm: a longitudinal prospective study

“…The neurological development of infants born preterm during the first months of life has been widely studied in infants with brain lesions or, more generally, at higher risk of developing an atypical outcome 4–7 . The Hammersmith Infant Neurological Examination (HINE) is one of the simplest neurological examinations for the early diagnosis of neurological impairment in both low‐ and high‐risk infants during the first 2 years of life 7–17 .…”

Brain microstructural antecedents of visual difficulties in infants born very preterm

“…Demographic and clinical variables for infants included in the final cohort and infants excluded are shown in Table 1 . Global brain abnormality score (as defined by Kidokoro et al, 2013 ) was used to assess structural injuries and delayed brain maturation for infants in our cohort (Median: 1, IQR: 4), as previously described ( Harpster et al 2021 ). 141 (73.8%) VPT infants had no injury on sMRI, 34 (17.8%) had mild injury, 8 (4.2%) had moderate injury, and 8 (4.2%) had severe injury.…”