Photodynamic therapy associated final irrigation in root canals of the primary teeth

Martins, Camila Regina Maciel; Andrade, Marcelo Ventura de; Carvalho, Ana Paula de; Pereira, Rafael Martins Afonso; Bresolin, Carmela Rampazzo; Mello‐Moura, Anna Carolina Volpi; Imparato, José Carlos Pettorossi

doi:10.1016/j.pdpdt.2021.102182

Cited by 7 publications

(7 citation statements)

References 24 publications

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“…Öter et al [31] assessed the efficacy of PDT with 670 nm laser and tolonium chloride as PS against a 1-week biofilm of E. faecalis in primary root canals; they showed lower efficacy of this modality compared with 2.5% NaOCl, which was in agreement with present findings. However, another study by Martin et al [20] indicated that PDT with 660 nm laser and toluidine blue caused a greater reduction in E. faecalis count compared with chemomechanical preparation alone. Pinheiro et al [40] found that chemomechanical root canal preparation alone decreased intracanal biofilm in necrotic primary molars by 82% while using PDT as an adjunct resulted in 98% bacterial reduction, which was different from the percentage of reduction obtained in the present study.…”

Section: Discussionmentioning

confidence: 95%

“…Extracted primary mandibular second molars with a minimum of two-thirds of the root remaining were collected. Teeth with physiological resorption and internal or external pathologies were excluded after radiographic examination [20]. Teeth with a history of pulpotomy or pulpectomy and perforation of pulp chamber floor were also excluded after radiographic examination [21].…”

Section: Eligibility Criteriamentioning

confidence: 99%

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Antibacterial Efficacy of Cold Atmospheric Plasma, Photodynamic Therapy with Two Photosensitizers, and Diode Laser on Primary Mandibular Second Molar Root Canals Infected with Enterococcus faecalis: An In Vitro Study

Haghighi

Azizi

Vatanpour

et al. 2023

International Journal of Dentistry

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Objectives. This study aimed to compare the antibacterial efficacy of cold atmospheric plasma (CAP), photodynamic therapy (PDT) with two photosensitizers (PSs), and diode laser for disinfection of primary mandibular second molar root canals infected with Enterococcus faecalis (E. faecalis). Materials and Methods. In this in vitro experimental study, 50 primary second primary molars underwent chemomechanical preparation of root canals. The root canals were then inoculated with E. faecalis. After 3 weeks of incubation, the teeth were randomly assigned to five groups of CAP, 940 nm diode laser, PDT with 445 nm laser and curcumin PS, PDT with 660 nm laser and methylene blue (MB) PS, and 2.5% sodium hypochlorite (NaOCl). Samples were collected from the vortexed root canals and cultured on agar, and the number of colonies was counted. Data were analyzed by one-way analysis of variance. Results. The percentage of reduction in bacterial count was significantly different among the study groups ( P < 0.001 ). The highest reduction in bacterial count was noted in 2.5% NaOCl and the lowest in 940 nm diode laser group. The difference in bacterial count reduction between 445 nm laser + curcumin and 660 nm laser + MB ( P = 0.989 ), and CAP and NaOCl ( P = 1.000 ) groups was not significant. Conclusion. CAP was found to be more effective than PDT and diode laser as an adjunct to mechanical root canal disinfection of primary molars for elimination of E. faecalis and can serve as an alternative to 2.5% NaOCl irrigation.

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Section: Discussionmentioning

confidence: 95%

Section: Eligibility Criteriamentioning

confidence: 99%

Antibacterial Efficacy of Cold Atmospheric Plasma, Photodynamic Therapy with Two Photosensitizers, and Diode Laser on Primary Mandibular Second Molar Root Canals Infected with Enterococcus faecalis: An In Vitro Study

Haghighi

Azizi

Vatanpour

et al. 2023

International Journal of Dentistry

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“…24 From this perspective, different supplementary methods for improving root canal disinfection in primary teeth have been investigated, 25 and PDT has shown significantly positive in vitro results on microbiological load reduction. [26][27][28] Additionally, case reports on PDT application in primary teeth infections discussed some possible benefits, such as improving the outcome of traumatized primary teeth 29,30 and potentially reducing microbiological load, thus improving the therapy prognosis. 31,32 It is noteworthy that case reports represent the lowest evidence possible and should not be used to justify the use of an experimental intervention;…”

Section: Discussionmentioning

confidence: 99%

“…This type of treatment, however, can be a challenging task for the clinician since primary teeth present physiological, morphological, and behavioral aspects such as root resorptions, complex root anatomy, and difficult patient management 24 . From this perspective, different supplementary methods for improving root canal disinfection in primary teeth have been investigated, 25 and PDT has shown significantly positive in vitro results on microbiological load reduction 26–28 . Additionally, case reports on PDT application in primary teeth infections discussed some possible benefits, such as improving the outcome of traumatized primary teeth 29,30 and potentially reducing microbiological load, thus improving the therapy prognosis 31,32 .…”

Section: Discussionmentioning

confidence: 99%

Photodynamic therapy in the root canal treatment of primary teeth: A systematic review of clinical trials

Araújo

Gobbo

Silva

et al. 2023

Int J Paed Dentistry

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BackgroundDental caries is the most common oral disease worldwide, and it is estimated to affect 2.3 billion people, with at least 530 million of them being schoolchildren with decayed primary teeth. This condition can rapidly evolve into irreversible pulp inflammation and pulp necrosis and thus requiring endodontic intervention. Photodynamic therapy (PDT) is a supplementary method to conventional pulpectomy and is used to improve the protocol used for disinfection.AimThe main objective of this study was to evaluate through a systematic review the efficacy of supplementary PDT on the pulpectomy of primary teeth. This review was registered a priori on the PROSPERO database (CRD42022310581).DesignTwo independent and blinded reviewers carried out a comprehensive search in five databases: PubMed, Cochrane, Scopus, Embase, and Web of Science. Eligible studies were randomized and nonrandomized clinical trials that evaluated in vivo microbiological load or clinical outcomes after using supplementary PDT in infected primary teeth.ResultsAfter the selection process, four studies met the inclusion criteria and were included in this study. Data regarding the sample characteristics and PDT protocols were retrieved. All included trials used phenothiazinium salts as photosensitizer agents. Only one study observed a significant difference in the in vivo microbiological load reduction outcome when performing PDT on primary teeth. The remaining studies all discussed the possible benefits of this intervention; however, none observed a significant difference in this outcome.ConclusionIn this systematic review, moderate‐to‐low certainty of the available evidence was observed, and thus, no significant conclusions can be drawn from the findings.

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“…El tratamiento endodóntico está basado en eliminar mecánicamente el tejido pulpar necrótico y desinfectar químicamente el sistema de conductos radiculares (1). Los microorganismos y sus subproductos metabólicos son agentes etiológicos de las patologías endodónticas más frecuentes; por lo tanto, eliminar o reducir los microorganismos dentro del sistema de conductos radiculares debe ser uno de los objetivos principales para lograr el éxito del tratamiento (2).…”

Section: Introductionunclassified

Photodynamic therapy, a new trend in endodontics for the removal of Enterococcus faecalis

Calderón Augusto,

Cassana Rojas,

Villar Zapata

et al. 2024

Rev Estomatol Herediana.

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La desinfección se consigue mediante procedimientos como la instrumentación, la irrigación y la medicación intraconducto; sin embargo, estos no son suficientes, ya que diversos estudios han reportado al E. faecalis como uno de los microorganismos persistentes con mayor prevalencia en tratamientos de conductos que no han conseguido la curación de los tejidos periapicales. Se ha tratado de mejorar los protocolos de desinfección incluyendo diferentes herramientas tecnológicas como en el caso de la terapia fotodinámica, la cual utiliza una fuente de luz y sustancias fotosensibilizantes que favorecen el proceso de eliminación de las bacterias remanentes dentro del sistema de conductos radiculares. La presente revisión de literatura científica profundiza en la importancia clínica de la terapia fotodinámica y su efecto en la desinfección e inhibición del E. faecalis dentro del sistema de conductos, lo cual se ha vuelto una pieza clave para el éxito del tratamiento endodóntico.

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Photodynamic therapy associated final irrigation in root canals of the primary teeth

Cited by 7 publications

References 24 publications

Antibacterial Efficacy of Cold Atmospheric Plasma, Photodynamic Therapy with Two Photosensitizers, and Diode Laser on Primary Mandibular Second Molar Root Canals Infected with Enterococcus faecalis: An In Vitro Study

Antibacterial Efficacy of Cold Atmospheric Plasma, Photodynamic Therapy with Two Photosensitizers, and Diode Laser on Primary Mandibular Second Molar Root Canals Infected with Enterococcus faecalis: An In Vitro Study

Photodynamic therapy in the root canal treatment of primary teeth: A systematic review of clinical trials

Photodynamic therapy, a new trend in endodontics for the removal of Enterococcus faecalis

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