Low agreement between kidney volume and kidney length z-scores

Torres‐Canchala, Laura; Rengifo, Martin; Filler, Guido; Arias, Juan Carlos; Ramírez, Óscar; Restrepo, Juan Guillermo

doi:10.1007/s00467-020-04836-5

Cited by 10 publications

(8 citation statements)

References 23 publications

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“…The differences between the left and right kidneys warrant further study. 8 For the entire pediatric age range, we agree with Marzuillo et al 5 that only height be used to assess normal kidney length using the Obrycki normative values. 6 We urgently need to confirm the BSA equations or develop new ones in large individuals.…”

Section: Discussionsupporting

confidence: 85%

“…The left kidney tends to be more elongated, likely owing to the usually larger liver pushing the right kidney downward, making it more plump. 8 The authors performed a Pearson correlation analysis that highlights the difference between the right and left kidneys whereby the right kidney was best correlated with the participant's height, whereas the left kidney was best correlated with their weight. They also performed Box-Cox transformations to normality for height and BSA for both the right and left kidneys.…”

Section: Introductionmentioning

confidence: 99%

“…7 Kidney volumes and kidney length have been shown to have low agreement in the evaluation of prematurely born children. 8 In this context, we are delighted to see the recent publication with new normative data for both kidney length and kidney volume by Tsehay and Seyoum in the Canadian Journal of Kidney Health and Disease . 9…”

Section: Introductionmentioning

confidence: 99%

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Editorial: There Is Still a Need for Kidney Volume Reference Intervals in Large Children, Adolescents, and Young Adults

Filler

2023

Can J Kidney Health Dis

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Section: Discussionsupporting

confidence: 85%

Section: Introductionmentioning

confidence: 99%

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Editorial: There Is Still a Need for Kidney Volume Reference Intervals in Large Children, Adolescents, and Young Adults

Filler

2023

Can J Kidney Health Dis

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“…Unfortunately, low agreement between kidney volume and KL has been demonstrated [31][32][33]. As a future perspective, it could be interesting to study the performance of kidney volume to precisely assess kidney size in children and adolescents with OW/OB.…”

Section: Discussionmentioning

confidence: 99%

Body surface area-based kidney length percentiles misdiagnose small kidneys in children with overweight/obesity

et al. 2022

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Background We evaluated the diagnostic performance of height-, age- and body surface area (BSA)-based kidney length (KL) percentiles in the identification of at least one small kidney (KL < 3rd) and in the prediction of reduced estimated glomerular filtration rate (eGFR) and/or elevated blood pressure (BP) in children with and without overweight (OW)/obesity(OB). Methods In this cross-sectional study, 744 apparently healthy children (mean age 8.3 years) were recruited in a primary care setting. Clinical data were collected, and serum creatinine and KL were measured. Height-, age- and BSA-based percentiles of KL were calculated and the association of at least one small kidney per subject with reduced eGFR and/or elevated BP was explored by logistic regression. Results Two hundred fifty-seven out of seven hundred forty-four (34.5%) subjects were OW/OB and 127 (17.1%) had reduced eGFR or elevated BP. In separate analyses in children with OW/OB, the KL percentiles calculated on the basis of BSA were lower compared with height- and age-based KL percentiles. Consequently, the prevalence of a small kidney was significantly higher when evaluating percentiles of KL based on BSA compared with other percentiles. In logistic regression analysis, a small kidney was significantly associated with reduced eGFR and/or elevated BP only when using height-based KL percentiles. The KL percentiles according to BSA for the ideal weight (iBSA) showed similar performance compared with height-based percentiles. No differences in the diagnostic performance of different percentiles were found in children with normal weight. Conclusions BSA-based percentiles underestimate KL in children with OW/OB. In these subjects, the use of height-based or iBSA-based percentiles should be preferred. Graphical abstract

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“…The most accessible were those of ultrasound, which gave rise to studies that entailed kidney measurements according to age and sex in each month and year in pediatrics ( 50 ), although not always specifying in the study sample the variables that would refer to nutritional status, blood pressure, and proteinuria of the healthy children ( 51 , 52 ).…”

Section: Possible Causes For the Appearance Of Ncds In Adultsmentioning

confidence: 99%

Low Birthweight as a Risk Factor for Non-communicable Diseases in Adults

Bianchi

Restrepo

2022

Front. Med.

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According to studies undertaken over the past 40 years, low birthweight (LBW) is not only a significant predictor of perinatal death and morbidity, but also increases the risk of chronic non-communicable diseases (NCDs) in adulthood. The purpose of this paper is to summarize the research on LBW as a risk factor for NCDs in adults. The Barker hypothesis was based on the finding that adults with an LBW or an unhealthy intrauterine environment, as well as a rapid catch-up, die due to NCDs. Over the last few decades, terminology such as thrifty genes, fetal programming, developmental origins of health and disease (DOHaD), and epigenetic factors have been coined. The most common NCDs include cardiovascular disease, diabetes mellitus type 2 (DMT2), hypertension (HT), dyslipidemia, proteinuria, and chronic kidney disease (CKD). Studies in mothers who experienced famine and those that solely reported birth weight as a risk factor for mortality support the concept. Although the etiology of NCD is unknown, Barry Brenner explained the notion of a low glomerular number (nGlom) in LBW children, followed by the progression to hyperfiltration as the physiopathologic etiology of HT and CKD in adults based on Guyton's renal physiology work. Autopsies of several ethnic groups have revealed anatomopathologic evidence in fetuses and adult kidneys. Because of the renal reserve, demonstrating renal function in proportion to renal volume in vivo is more difficult in adults. The greatest impact of these theories can be seen in pediatrics and obstetrics practice.

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Low agreement between kidney volume and kidney length z-scores

Cited by 10 publications

References 23 publications

Editorial: There Is Still a Need for Kidney Volume Reference Intervals in Large Children, Adolescents, and Young Adults

Editorial: There Is Still a Need for Kidney Volume Reference Intervals in Large Children, Adolescents, and Young Adults

Body surface area-based kidney length percentiles misdiagnose small kidneys in children with overweight/obesity

Low Birthweight as a Risk Factor for Non-communicable Diseases in Adults

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