Effectiveness and equity of continuous subcutaneous insulin infusions in pediatric type 1 diabetes: A systematic review and meta-analysis of the literature

Santos, Tiago Jeronimo Dos; Campos, Juan Donado; Argente, Jesús; Rodríguez‐Artalejo, Fernando

doi:10.1016/j.diabres.2020.108643

Cited by 16 publications

(12 citation statements)

References 64 publications

(85 reference statements)

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“…6 The use of insulin pump has been shown to be safe and may enable patients with T1D to reach glycemic targets with reduction of recurrent and severe hypoglycemic events and an improved quality of life. [20][21][22][23][24][25][26]40 The increased use of CGM modified the management of T1D in these patients improving glycemic control and reducing glycemic variability. 20,24,27,28,30 Moreover, recent international guidelines recommend early adoption of CGM for all children and adolescents with T1D.…”

Section: Bmi-sdsmentioning

confidence: 99%

Association of the use of diabetes technology withHbA1candBMI‐SDSin an international cohort of children and adolescents with type 1 diabetes: TheSWEETproject experience

et al. 2021

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Section: Bmi-sdsmentioning

confidence: 99%

Association of the use of diabetes technology withHbA1candBMI‐SDSin an international cohort of children and adolescents with type 1 diabetes: TheSWEETproject experience

et al. 2021

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“…As this is a novel review topic, the types of interventions that will be reported in the literature is not yet clear. Therefore, we have included a wide range of potential interventional components, which have been selected directly from the 2015 EPOC taxonomy 16 , with the notable addition of patient/carer education and exclusion of interventions which are solely comprised of continuous/flash glucose monitoring or insulin pump-related technologies, given the array of high quality systematic reviews available in the field [17][18][19][20] .…”

Section: Types Of Interventionsmentioning

confidence: 99%

Effectiveness of quality improvement strategies for type 1 diabetes in children and adolescents: a systematic review protocol

et al. 2021

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Introduction: Optimal glycaemic control is often a challenge in children and adolescents with type 1 diabetes (T1D). Implementation of patient, clinician or organisation-targeted quality improvement (QI) strategies has been proven to be beneficial in terms of improving glycaemic outcomes in adults living with diabetes. This review aims to assess the effectiveness of such QI interventions in improving glycaemic control, care delivery, and screening rates in children and adolescents with T1D. Methods and analysis: MEDLINE, EMBASE, CINAHL and Cochrane CENTRAL databases will be searched for relevant studies up to January 2021. Trial registries, ClinicalTrials.gov and ICTRP, will also be explored for any ongoing trials of relevance. We will include trials which examine QI strategies as defined by a modified version of the Cochrane Effective Practice and Organisation of Care 2015 Taxonomy in children (<18 years) with a diagnosis of T1D. The primary outcome to be assessed is glycated haemoglobin (HbA1c), although a range of secondary outcomes relating to clinical management, adverse events, healthcare engagement, screening rates and psychosocial parameters will also be assessed. Our primary intention is to generate a best-evidence narrative to summarise and synthesise the resulting studies. If a group of studies are deemed to be highly similar, then a meta-analysis using a random effects model will be considered. Cochrane Risk of Bias 1.0 tool will be applied for quality assessment. All screening, data extraction and quality assessment will be performed by two independent researchers. Dissemination: The results of this review will be disseminated through peer-reviewed publication in order to inform invested partners (e.g., Paediatric Endocrinologists) on the potential of QI strategies to improve glycaemic management and other related health outcomes in children with T1D, thereby guiding best practices in the outpatient management of the disorder. PROSPERO registration number: CRD42021233974 (28/02/2021).

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“…While diabetic ketoacidosis (DKA) is of theoretical concern on CSII given the sole use of rapid-acting insulin, recent studies do not demonstrate significant differences in rates of DKA between CSII and MDI. This risk estimate is limited due to risk of bias in most clinical studies [92]…”

Section: Traditional "Open Loop" Insulin Pumpsmentioning

confidence: 99%

“…Additionally, equity in diabetes care and care delivery needs to be addressed, as related variables are often absent from trials [92]. Despite an overall rise in insulin pump use (which is associated with improvements in quality of life), non-Hispanic Black youth, Hispanic youth, and American Indian/Alaskan Native youth are significantly less likely to be on insulin pump therapy independent of socioeconomic status [177].…”

Section: Caveatsmentioning

confidence: 99%

The Evolution of Insulin Administration in Type 1 Diabetes

Pinnaro¹,

Tansey²

2021

JDM

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Effectiveness and equity of continuous subcutaneous insulin infusions in pediatric type 1 diabetes: A systematic review and meta-analysis of the literature

Cited by 16 publications

References 64 publications

Association of the use of diabetes technology withHbA1candBMI‐SDSin an international cohort of children and adolescents with type 1 diabetes: TheSWEETproject experience

Association of the use of diabetes technology withHbA1candBMI‐SDSin an international cohort of children and adolescents with type 1 diabetes: TheSWEETproject experience

Effectiveness of quality improvement strategies for type 1 diabetes in children and adolescents: a systematic review protocol

The Evolution of Insulin Administration in Type 1 Diabetes

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