Management of borderline ovarian tumours during pregnancy: Results of a French multi-centre study

Zilliox, M.; Lecointre, Lise; Azaïs, Henri; Ballester, Marcos; Bendifallah, Sofiane; Bolze, Pierre‐Adrien; Bourdel, Nicolas; Bricou, Alexandre; Canlorbe, Geoffroy; Carcopino, Xavier; Collinet, Pierre; Coutant, Charles; Dabi, Yohann; Dion, Ludivine; Gauthier, Tristan; Graesslin, Olivier; Huchon, Cyrille; Koskas, Martin; Lavoué, Vincent; Mezzadri, M.; Mimoun, Camille; Ouldamer, Lobna; Raimond, Émilie; Touboul, Cyril; Lapointe, Marise; Akladios, Chérif

doi:10.1016/j.ejogrb.2020.11.033

Cited by 12 publications

(15 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Pelvic ultrasonography is the gold standard and first-line examination for the examination of adnexal masses during pregnancy ( 3 ). Among the 17 patients, 13 (76.5%) showed adnexal masses.…”

Section: Resultsmentioning

confidence: 99%

“…A French multicenter study by Zillioxd et al. also shows that conservative surgery is safe and effective for patients with pregnancy complicated by borderline ovarian tumors ( 3 ). The neonatal Apgar score was related to gestational age and obstetric complications, but not to borderline ovarian tumors.…”

Section: Discussionmentioning

confidence: 98%

“…Due to the particularity of pregnancy and the limitations and incompleteness of preoperative examination, the diagnosis of pregnancy complicated with an ovarian borderline tumor is more difficult. Expert consensus also does not recommend the use of any tumor markers to diagnose BOT during pregnancy ( 3 ).…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Clinical Analysis of 17 Cases of Borderline Ovarian Tumors During Pregnancy

Wang

et al. 2022

Front. Oncol.

View full text Add to dashboard Cite

ObjectiveThe study retrospectively analyzed the clinical characteristics and prognosis of 17 cases of pregnancy complicated by borderline ovarian tumors to provide help for clinical workers.Materials and MethodsThe clinicopathological data of 17 patients with ovarian borderline tumors during pregnancy at the Shengjing Hospital of China Medical University from January 2015 to June 2021 were collected and analyzed retrospectively. The average age of the patients was 31.82 years (25–45 years), the average number of pregnancies was 2.06 times (1–6 times), and the average number of births was 0.41 times (0–1 time).ResultsAmong the 17 patients, 4 were diagnosed in the first trimester, 2 in the second trimester, and 11 in the third trimester. Most of the first symptoms were cysts, cyst enlargement, or cyst rupture. Among them, 3 cases (1 in the first trimester and 2 in the second trimester) continued pregnancy after a conservative operation, 9 cases underwent cesarean section and a conservative operation simultaneously, and the mother and child had a good outcome. Two cases underwent conservative operations and induced abortion, and 1 case underwent an ectopic pregnancy operation at the same time. The prognosis of the patients was good without recurrence.ConclusionPreoperative diagnosis of borderline ovarian tumors in pregnancy is delayed, and imaging and tumor markers are not specific. The coincidence rate between intraoperative frozen pathology and postoperative paraffin pathology was not high. Borderline tumors are mainly treated by surgery, and the prognosis for mothers and infants is good.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 98%

See 1 more Smart Citation

Clinical Analysis of 17 Cases of Borderline Ovarian Tumors During Pregnancy

Wang

et al. 2022

Front. Oncol.

View full text Add to dashboard Cite

show abstract

“…Apart from the possible effect of neoadjuvant chemotherapy, we may argue that high progesterone levels during pregnancy have stabilized the progesterone receptor (PR)-positive low-grade serous ovarian cancer, similarly to the excellent results obtained with letrozole in the adjuvant setting 12 . On the contrary, although data are lacking on low-grade serous ovarian cancer during pregnancy, serous borderline ovarian tumors may exhibit more aggressive features during pregnancy that might have been induced by higher progesterone levels 13 . Therefore, neoadjuvant chemotherapy should currently not be avoided.…”

Section: Case Presentationmentioning

confidence: 98%

Low-grade serous ovarian cancer in pregnancy

Peters

Testa

Arciuolo

et al. 2022

Int J Gynecol Cancer

View full text Add to dashboard Cite

“…Fortunately and due to routine antenatal ultrasound, adnexal malignancies are usually detected at an early stage during pregnancy [ 21 ]. In cases with borderline tumors of the ovary, conservative surgery should be performed during pregnancy and additional staging surgery should be performed after delivery ( Table 1 ) [ 7 , 22 ]. In epithelial ovarian cancer and if the disease is limited to the ovary, surgical staging can be performed either before 22 weeks of gestation or after delivery ( Table 1 ) [ 7 ].…”

Section: Therapeutic Principles In Women With Cancer In Pregnancymentioning

confidence: 99%

Cancer and Pregnancy: A Comprehensive Review

Schwab

Anić

Hasenburg

2021

Cancers

View full text Add to dashboard Cite

Cancer diagnosis and treatment in pregnant women is a challenging situation. A multidisciplinary network of specialists is required to guide both, the expecting mother and the unborn child through the diagnostic workup and the cytotoxic therapy, by balancing the respective risks and benefits. Tumor entity, stage, biology and gestational week at diagnosis determine the appropriate approach. As premature delivery emerged as one of the main risk factors for adverse long-term outcome of the progeny, it should be avoided, if reasonable from the oncological perspective. This article offers a comprehensive review with respect to the various aspects of cancer in pregnancy.

show abstract

Management of borderline ovarian tumours during pregnancy: Results of a French multi-centre study

Cited by 12 publications

References 21 publications

Clinical Analysis of 17 Cases of Borderline Ovarian Tumors During Pregnancy

Clinical Analysis of 17 Cases of Borderline Ovarian Tumors During Pregnancy

Low-grade serous ovarian cancer in pregnancy

Cancer and Pregnancy: A Comprehensive Review

Contact Info

Product

Resources

About