2021
DOI: 10.1128/jb.00568-20
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The Two TpsB-Like Proteins in Anabaena sp. Strain PCC 7120 Are Involved in Secretion of Selected Substrates

Abstract: The outer membrane of Gram-negative bacteria acts as an initial diffusion barrier that shields the cell from the environment. It contains many membrane-embedded proteins required for functionality of this system. These proteins serve as solute and lipid transporters or as machines for membrane insertion or secretion of proteins. The genome of Anabaena sp. PCC 7120 codes for two outer membrane transporters termed TpsB1 and TpsB2. Those belong to the family of the two-partner secretion system proteins which are … Show more

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Cited by 3 publications
(1 citation statement)
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“…LPS biogenesis takes place at the cytoplasmic side of the inner membrane with the production of Lipid A moiety, which is synthesized by Lpx (lipoxygenase) proteins (Anderson & Raetz, 1987;Wyckoff et al, 1998;Raetz et al, 2009). Subsequently, the core oligosaccharide is attached to the lipid A by Waa protein to form the lipid A-core oligosaccharide complex, which is flipped to the periplasmic side of the inner membrane by MsbA with the function of an ATP-binding cassette transporter (ABC transporter) located at the inner membrane (Karow & Georgopoulos, 1993;Zhou et al, 1998;Raetz & Whitfield, 2002;Doerrler et al, 2004;.…”
Section: The Biogenesis Of Lps In E Colimentioning
confidence: 99%
“…LPS biogenesis takes place at the cytoplasmic side of the inner membrane with the production of Lipid A moiety, which is synthesized by Lpx (lipoxygenase) proteins (Anderson & Raetz, 1987;Wyckoff et al, 1998;Raetz et al, 2009). Subsequently, the core oligosaccharide is attached to the lipid A by Waa protein to form the lipid A-core oligosaccharide complex, which is flipped to the periplasmic side of the inner membrane by MsbA with the function of an ATP-binding cassette transporter (ABC transporter) located at the inner membrane (Karow & Georgopoulos, 1993;Zhou et al, 1998;Raetz & Whitfield, 2002;Doerrler et al, 2004;.…”
Section: The Biogenesis Of Lps In E Colimentioning
confidence: 99%