Solubilization of tadalafil using a tartaric acid and chitosan-based multi-system

Development and evaluation of febuxostat solid dispersion through screening method

“…In previous studies, tadalafil-SD formulation was performed to find the main factors. PVP/VA S-630 was important to improve the pre-dissolution (%) of tadalafil in tadalafil-SD formulation (consist of chitosan, Aerosil®200 and PVP/VA S-630) ( Sohn and Choi, 2021b ). Additionally, the naftopidil-SD formulation was confirmed as the key factor.…”

“…The reason for performing the Febux solubility test is to select choose which polymer and pH substance to use. Thus, the solubility of Febux was evaluated in 1% (w/v) polymeric solutions, DW, and universal buffers (pH 1.0, 4.0, 7.0, and 10.0)( Sohn and Choi, 2021b ). However, the pH4 buffer and Soluplus® prepared for the above solubility measurements were excluded due to UV–vis interference.…”

Investigating in-vitro functionality and in-vivo taste assessment of eco-friendly Tadalafil Pastilles

“…TDL release was statistically calculated, and its relation with time (min.) was observed [ [78] , [79] , [80] ].…”

Kinetic Modeling of Glucose Oxidation to Tartaric Acid over Monometallic Pt/TiO2 and Bimetallic AuPt/TiO2 Catalysts: Role of Bimetals on C–H and C–C Cleavages

“…15−17 Enzyme catalysis is another effect way to produce TA, owing to high substrate conversion and product purity. 18,19 Specifically, maleic acid is epoxidized to cisepoxy succinic acid, after which utilizes relevant hydrolase produced by microorganisms to obtain TA. 20,21 However, biotransformation technologies still suffer from low productivity.…”

“… , Traditionally, it was obtained as a crude solid byproduct from wine fermentation. , The productivity and quality were strongly influenced by the growth of grapes and climatic conditions . A chemical synthesis method using maleic anhydride has been found to significant discharge wastewater containing heavy metals. − Enzyme catalysis is another effect way to produce TA, owing to high substrate conversion and product purity. , Specifically, maleic acid is epoxidized to cis -epoxy succinic acid, after which utilizes relevant hydrolase produced by microorganisms to obtain TA. , However, biotransformation technologies still suffer from low productivity. , An alternative method involving direct synthesis of TA from glucose oxidation using bimetallic AuPt/TiO 2 catalysts has been reported recently. , This synthetic method provides a promising route for the production of various downstream polymers and pharmaceutical products. − …”