The associations of air pollution and socioeconomic factors with esophageal cancer in China based on a spatiotemporal analysis

Jing, Jing; Guo, Wenwen; Guo, Xiaochuan; Hu, Wenbiao; Qi, Xin; Wei, Wenqiang; Zhuang, Guihua

doi:10.1016/j.envres.2020.110415

Cited by 15 publications

(12 citation statements)

References 65 publications

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“…We found that long-term exposure to PM2.5 was significantly associated with the increased ECI, which was consistent with our previous findings (Li et al, 2020). Similarly, a cross-sectional study from China observed multiple air pollutants were an contributor for ECI after controlling other confounders (Huang et al, 2017).…”

Section: Discussionsupporting

confidence: 92%

The lag effect of exposure to PM2.5 on esophageal cancer in urban-rural areas across China

Peng

Guo

Jing

et al. 2021

Environ Sci Pollut Res

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Long-term exposure to PM2.5 pollution is a significant health concern and increases risks for cancers in China. However, the studies regarding the effect of PM2.5 and esophageal cancer incidence (ECI) among urban-rural areas are limited. In this study, we examined the sex-and areaspecific association between long-term exposure to PM2.5 and ECI, as well as explored the corresponding lag effects on ECI using a geographical weighted Poisson regression. We found that each 10 ug/m 3 PM2.5 caused ECI risk increases of 1.22% (95% CI: 1.09%, 1.36%) and 1.90% (95% CI: 1.66%, 2.14%) for males and females after covariates controlled, respectively, during the study period. Moreover, the higher 0.17% and 0.64% incidence risks for males and females in rural areas than urban areas, as well as a larger lag period in rural areas, respectively. In addition, higher risks for both sexes appeared in north, northwestern, and east China. The findings indicated that long-term exposure to PM2.5 was significantly associated with increased risks for ECI, which reinforce a comprehensive understanding for ECI related to PM2.5.

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Section: Discussionsupporting

confidence: 92%

The lag effect of exposure to PM2.5 on esophageal cancer in urban-rural areas across China

Peng

Guo

Jing

et al. 2021

Environ Sci Pollut Res

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“…The World Health Organization (WHO) believes that environmental pollution is the biggest threat to human health. Epidemiology has also confirmed the relationship between health problems such as tumors, respiratory diseases, cardiovascular and cerebrovascular diseases, and environmental pollution ( 32 – 34 ). From the perspective of social factors, the length of education and education funding are also closely related to the health of residents.…”

Section: Methodsmentioning

confidence: 88%

Study of the Economic, Environmental, and Social Factors Affecting Chinese Residents' Health Based on Machine Learning

Pan²,

Meng³

et al. 2022

Front. Public Health

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The Healthy China Strategy puts realistic demands for residents' health levels, but the reality is that various factors can affect health. In order to clarify which factors have a great impact on residents' health, based on China's provincial panel data from 2011 to 2018, this paper selects 17 characteristic variables from the three levels of economy, environment, and society and uses the XG boost algorithm and Random forest algorithm based on recursive feature elimination to determine the influencing variables. The results show that at the economic level, the number of industrial enterprises above designated size, industrial added value, population density, and per capita GDP have a greater impact on the health of residents. At the environmental level, coal consumption, energy consumption, total wastewater discharge, and solid waste discharge have a greater impact on the health level of residents. Therefore, the Chinese government should formulate targeted measures at both economic and environmental levels, which is of great significance to realizing the Healthy China strategy.

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“…The positive association between ambient PM 2.5 and UADT cancer risk found in this study is consistent with findings from some Asian studies that showed positive associations between ambient PM 2.5 and different subsites of UADT cancers, but the PM 2.5 concentrations were reported to be much higher than the ones reported in the United States with means or medians above 30 μg/m 3 (Table S4). [24][25][26][27][28][29][30] For Taiwanese residents, increased incidence rates of nasopharyngeal cancer (hazard ratio [HR] = 1.97, 95% CI: 1.13-3.43) and oral cancer (OR = 1.43, 95% CI: 1.17-1.74) were reported among those living in areas within the highest compared to the lowest quartile of PM 2.5 exposure. 24,27 An elevated mortality rate of upper digestive tract cancer due to PM 2.5 was observed in Hong Kong (HR = 1.42 per 10 μg/m 3 increase, 95% CI: 1.06-1.89), 29 and the incidence rate of esophageal cancer was increased in China by at least 1.03% for each 1-μg/m 3 increase in PM 2.5 .…”

Section: Discussionmentioning

confidence: 99%

Association between ambient exposure to PM_2.5 and upper aerodigestive tract cancer in Los Angeles

Fang,

Ritz,

Rao

et al. 2024

Intl Journal of Cancer

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Fine particulate matter (PM2.5) contains carcinogens similar to those generated by tobacco smoking, which may increase the risks of developing smoking‐related cancers, such as upper aerodigestive track (UADT) cancers, for both smokers and never‐smokers. Therefore, it is imperative to understand the relation between ambient PM2.5 exposure and risk of UADT cancers. A population‐based case–control study involving 565 incident UADT cancer cases and 983 controls was conducted in Los Angeles County from 1999 to 2004. The average residential PM2.5 concentration 1 year before the diagnosis date for cases and the reference date for controls was assessed using a chemical transport model. The association between ambient PM2.5 and the UADT cancers was estimated by unconditional logistic regression, adjusting for confounders at the individual and block‐group level. Stratified analyses were conducted by sex, tobacco smoking status and UADT subsites. We also assessed the interaction between PM2.5 and tobacco smoking on UADT cancers. PM2.5 concentrations were associated with an elevated odds of UADT cancers (adjusted odds ratio = 1.21 per interquartile range [4.5 μg/m3] increase; 95% confidence interval: 1.02, 1.44). The association between PM2.5 and UADT cancers was similar across UADT subsites, sex and tobacco smoking status. The interaction between PM2.5 and tobacco smoking on UADT cancers was approximately additive on the odds scale. The effect estimate for PM2.5 and UADT cancers was similar among never smokers. Our findings support the hypothesis that exposure to PM2.5 increases the risk of UADT cancers. Improvements in air quality may reduce the risk of UADT cancers.

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The associations of air pollution and socioeconomic factors with esophageal cancer in China based on a spatiotemporal analysis

Cited by 15 publications

References 65 publications

The lag effect of exposure to PM2.5 on esophageal cancer in urban-rural areas across China

The lag effect of exposure to PM2.5 on esophageal cancer in urban-rural areas across China

Study of the Economic, Environmental, and Social Factors Affecting Chinese Residents' Health Based on Machine Learning

Association between ambient exposure to PM_2.5 and upper aerodigestive tract cancer in Los Angeles

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The associations of air pollution and socioeconomic factors with esophageal cancer in China based on a spatiotemporal analysis

Cited by 15 publications

References 65 publications

The lag effect of exposure to PM2.5 on esophageal cancer in urban-rural areas across China

The lag effect of exposure to PM2.5 on esophageal cancer in urban-rural areas across China

Study of the Economic, Environmental, and Social Factors Affecting Chinese Residents' Health Based on Machine Learning

Association between ambient exposure to PM2.5 and upper aerodigestive tract cancer in Los Angeles

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Association between ambient exposure to PM_2.5 and upper aerodigestive tract cancer in Los Angeles