Facile and recyclable dopamine sensing by a label-free terbium(III) metal−organic framework

Wu, Ke-Yang; Chen, Ming; Huang, Nai-Hai; Li, Rong-Tian; Pan, Weilun; Zhang, Wenhua; Chen, Wenhua; Chen, Jinxiang

doi:10.1016/j.talanta.2020.121399

Cited by 18 publications

(4 citation statements)

References 42 publications

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“…The selectivity, sensitivity, and detection limit of the target biomolecule are strictly determined by the characteristics of electrode modifiers. Therefore, many researchers have devoted their efforts to designing and preparing various electrode modifiers, including, but not limited to nanoparticles [ 17 ], nanocomposite [ 18 ], metal-organic frameworks (MOFs) [ 19 , 20 , 21 ], carbon nanotubes [ 22 ], graphene, graphene oxide [ 23 ], coordination polymer [ 24 ], ionic liquid [ 4 ] and so on. Among these electrode modifiers, MOFs were used as excellent electrode modifiers due to their facile and environmentally friendly synthesis approaches, unique topological structure features and functions including permanently porous structure, uniform channels, large internal surface areas, thermal stability, nanometer-sized cavities, and excellent catalytic activity.…”

Section: Introductionmentioning

confidence: 99%

Construction of Electrochemical and Photoelectrochemical Sensing Platform Based on Porphyrinic Metal-Organic Frameworks for Determination of Ascorbic Acid

Zhang

et al. 2022

Nanomaterials

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Highly sensitive and specific detection of biomolecular markers is of great importance to the diagnosis and treatment of related diseases. Herein, Cu-TCPP@MOFs thin films were synthesized with tetrakis(4-carboxyphenyl) porphyrin (H2TCPP) as organic ligands and copper ions as metal nodes. The as-synthesized Cu-TCPP@MOFs thin films as electrode modifiers were used to modify the pre-treated glassy carbon electrode (GCE) and the electrochemical performances of Cu-TCPP@MOFs/GCE were evaluated by electrochemical impedance spectroscopy (EIS) and cyclic voltammetry (CV). Furthermore, as the working electrode, the constructed Cu-TCPP@MOFs/GCE was used for the investigation of ascorbic acid (AA) due to its outstanding electrocatalytic activities towards AA by several electrochemical methods, including cyclic voltammetry (CV), differential pulse voltammetry (DPV), and chronoamperometry (CA). The well-linear relationship was established based on different AA concentration ranges and the ideal detection limits (LOD) were obtained in the above-mentioned electrochemical methods, respectively. Furthermore, a Cu-TCPP MOFs@GCE sensing platform was used as a photoelectrochemical (PEC) sensor to quantitatively detect AA based on the strong absorption properties of Cu-TCPP ingredients in Cu-TCPP MOFs in a visible light band of 400~700 nm. PEC sensing platform based on Cu-TCPP@MOFs exhibited a more extensive linear concentration range, more ideal detection limit, and better sensitivity relative than the other electrochemical methods for AA. The well linear regression equations were established between the peak current intensity and AA concentrations in different electrochemical technologies, including CV, DPV, and CA, and PEC technology. AA concentration ranges applicable to various electrochemical equations were as follows: 0.45~2.10 mM of CV, 0.75~2.025 mM of DPV, 0.3~2.4 mM of CA, 7.5~480 μM of PEC, and the corresponding detection limits for AA were 1.08 μM (S/N = 3), 0.14 μM (S/N = 3), 0.049 μM (S/N = 3), and 0.084 nA/μM. Moreover, the proposed Cu-TCPP MOFs@GCE electrochemical and photoelectrochemical sensing platform was applied to determine the AA concentration of a real human serum sample; the results reveal that Cu-TCPP MOFs@GCE sensing platform could accurately determine the concentration of AA of the human serum under other potential interferences contained in the human serum samples.

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Section: Introductionmentioning

confidence: 99%

Construction of Electrochemical and Photoelectrochemical Sensing Platform Based on Porphyrinic Metal-Organic Frameworks for Determination of Ascorbic Acid

Zhang

et al. 2022

Nanomaterials

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“…Many efforts have been dedicated to developing glucose biosensors for this reason. Several biosensors have been created for monitoring glucose levels, categorized by detecting methods such as visible absorption spectrum 5 , uorescence spectrum 6 , and electrochemistry 7,8 .…”

Section: Introductionmentioning

confidence: 99%

Glucose oxidase coupling with pistol-like DNAzyme based colorimetric assay for sensitive glucose detection in tears and saliva

Fan,

Zhou,

Wang

2024

Preprint

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Measuring glucose levels in tears and saliva is important for diagnosing and predicting several diseases without the need for intrusive procedures. Detecting low concentrations of glucose with high sensitivity is still a significant difficulty. A simple visual method was created to assess glucose levels in tears and saliva by utilizing glucose oxidase (GOx) to catalyze glucose and pistol-like DNAzyme (PLDz) for signal amplification. Specifically, the β-D-glucose in samples acts as the initial molecule that is identified and catalyzed by GOx to produce gluconic acid and H2O2. H2O2 triggered the self-cleavage of PLDz, resulting in the activation of the “part b” sequence to initiate catalytic hairpin assembly (CHA) and release the DNAzyme section in H1 probe. The DNAzyme functions as a peroxidase mimic, catalyzing the TMB–H2O2 system and leading to an increase in observable signals. The proposed approach demonstrated a low limit of detection of 0.32 µM and a broad detection range. Moreover, the proposed approach was effectively used to detect glucose in tears and saliva samples, indicating potential for diagnosing hyperglycemia-related disorders in clinical settings.

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“…Concerning nanomedicine, MOFs have been widely used as carriers or substrates for theranostic applications (Deng et al., 2019 ; Wu et al., 2018 ; Zhang et al., 2016 ). The adjustable pore size, extraordinary surface area, and abundant diversity of structure entitle MOFs to separate small molecules (e.g., gas, peptides, ions), yet the development of MOFs for macromolecule separation is still challenging (Lin et al., 2019 ; Wu et al., 2021 ; Zhang et al., 2017 ). Recently, an antibodies‐assisted MOF platform has been developed for EV isolation, named Tim4@ILI‐01 (Zhang et al., 2021 ).…”

Section: Introductionmentioning

confidence: 99%

Rapid and efficient isolation platform for plasma extracellular vesicles: EV‐FISHER

Pan

Feng

Luo

et al. 2022

J of Extracellular Vesicle

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Extracellular vesicles (EVs) have found diverse applications in clinical theranostics. However, the current techniques to isolate plasma EVs suffer from burdensome procedures and limited yield. Herein, we report a rapid and efficient EV isolation platform, namely, EV-FISHER, constructed from the metal-organic framework featuring cleavable lipid probes (PO 4 3− -spacer-DNA-cholesterol, PSDC). The EV-FISHER baits EVs from plasma by cholesterol and separates them with an ordinary centrifuge. The captured EVs could be released and collected upon subsequent cleavage of PSDC by deoxyribonuclease I. We conclude that EV-FISHER dramatically outperforms the ultracentrifugation (UC) in terms of time (∼40 min vs. 240 min), isolation efficiency (74.2% vs. 18.1%), and isolation requirement (12,800 g vs. 135,000 g). In addition to the stable performance in plasma, EV-FISHER also exhibited excellent compatibility with downstream single-EV flow cytometry, enabling the identification of glypican-1 (GPC-1) EVs for early diagnosis, clinical stages differentiation, and therapeutic efficacy evaluation in breast cancer cohorts. This work portrays an efficient strategy to isolate EVs from complicated biological fluids with promising potential to facilitate EVs-based theranostics.

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Facile and recyclable dopamine sensing by a label-free terbium(III) metal−organic framework

Cited by 18 publications

References 42 publications

Construction of Electrochemical and Photoelectrochemical Sensing Platform Based on Porphyrinic Metal-Organic Frameworks for Determination of Ascorbic Acid

Construction of Electrochemical and Photoelectrochemical Sensing Platform Based on Porphyrinic Metal-Organic Frameworks for Determination of Ascorbic Acid

Glucose oxidase coupling with pistol-like DNAzyme based colorimetric assay for sensitive glucose detection in tears and saliva

Rapid and efficient isolation platform for plasma extracellular vesicles: EV‐FISHER

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