Maternal childhood adversity and inflammation during pregnancy: Interactions with diet quality and depressive symptoms

McCormack, Clare; Lauriola, Vincenzo; Feng, Tianshu; Lee, Seonjoo; Spann, Marisa; Mitchell, Anika; Champagne, Frances A.; Monk, Catherine

doi:10.1016/j.bbi.2020.09.023

Cited by 19 publications

(6 citation statements)

References 74 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…There is a growing body of research linking lifespan adversity and stress sensitization with prenatal stress biology. Recent studies have found that women's experiences with childhood maltreatment either related directly to dysregulated prenatal stress biology, including inflammatory processes (McCormack et al., 2021), hypothalamic‐pituitary‐adrenal axis functioning (Epstein et al., 2019; Khoury et al., 2019; Morrison et al., 2017; Stephens et al., 2020; Swales et al., 2018; Thomas et al., 2018), and placental corticotropin‐releasing hormone (Steine et al., 2020), or strengthened associations with adulthood adversity (Epstein et al., 2019; Swales et al., 2018). These biological processes are hypothesized mechanistic pathways through which stress can influence maternal and fetal health (Gitau et al., 1998; Steine et al., 2020); thus, these studies are vital to advancing perinatal healthcare.…”

Section: Introductionmentioning

confidence: 99%

Influences of adversity across the lifespan on respiratory sinus arrhythmia during pregnancy

Kaliush

Terrell

Vlisides‐Henry

et al. 2021

Developmental Psychobiology

View full text Add to dashboard Cite

There is limited understanding of factors across the lifespan that influence pregnant women's respiratory sinus arrhythmia (RSA), which could have implications for their health and offspring development. We examined associations among 162 English‐ and Spanish‐speaking pregnant women's childhood maltreatment history, emotion dysregulation, recent life stress, and resting RSA during the third trimester. Moderated mediation analyses indicated that more severe childhood maltreatment history (95% confidence interval (CI) [0.26, 0.63]) and higher emotion dysregulation (95% CI [0.001, 0.006]) predicted more stress during pregnancy, and childhood maltreatment history interacted with emotion dysregulation to predict resting RSA (95% CI [−0.04, −0.0003]). Exploratory analyses revealed that women's health‐related stress during pregnancy mediated the relation between emotion dysregulation and RSA regardless of childhood maltreatment severity (95% CI [−0.007, −0.002]). These findings suggest that women's resting RSA during pregnancy may reflect physical and emotional stress accumulation across the lifespan and that relations between early life adversity and prenatal psychophysiology may be buffered by protective factors, such as emotion regulation. In addition, these findings underscore the importance of distinguishing between types of prenatal stress. Given the implications for women's health and offspring development, we urge researchers to continue exploring factors associated with pregnant women's psychophysiology.

show abstract

Section: Introductionmentioning

confidence: 99%

Influences of adversity across the lifespan on respiratory sinus arrhythmia during pregnancy

Kaliush

Terrell

Vlisides‐Henry

et al. 2021

Developmental Psychobiology

View full text Add to dashboard Cite

show abstract

“…A first set of studies in trauma follow the thought style of biological embedding. Most of the studies place emphasis on childhood trauma and measure it using scales such as the Childhood Trauma Questionnaires (McCormack et al, 2021), the Comprehensive Trauma Interview Screen (Shenk et al, 2021), and the Risky Families Questionnaires (Carroll et al, 2013). Articles mention that deciphering the biological links be-tween trauma and specific adverse health outcomes may offer the pos-sibility of targeted prevention strategies for at-risk children (Carroll et al, 2013;Shenk et al, 2021).…”

Section: Discussionmentioning

confidence: 99%

Biological embedding vs. embodiment of social experiences: How these two concepts form distinct thought styles around the social production of health inequalities

Louvel¹,

Soulier²

2022

Social Science & Medicine

View full text Add to dashboard Cite

“…However, comparison of mental and physical health variables showed that our neuroimaging groups differed in dietary health behavior diet, p = .017, avoidance of tobacco and alcohol, p = .03, anxiety (STAI), p = .043, and perceived stress (PSST), p = .029. Groups also differed in WIDUS total score ( p = .009), an indirect screener for drug use that asks questions including history of traumatic events, which are known to alter physiological processes and the epigenome in lasting ways ( Buss et al, 2017 ; Gustafsson et al, 2017 ; McCormack et al, 2021 ; Scorza et al, 2020 ; Tottenham and Sheridan, 2009 ). Differences between comparison groups with potential to influence maternal biology and, in turn, fetal development are a notable limitation of this and prior neonatal neural studies.…”

Section: Discussionmentioning

confidence: 99%

Miswiring the brain: Human prenatal Δ9-tetrahydrocannabinol use associated with altered fetal hippocampal brain network connectivity

Thomason

Palopoli

Jariwala

et al. 2021

Developmental Cognitive Neuroscience

View full text Add to dashboard Cite

Increasing evidence supports a link between maternal prenatal cannabis use and altered neural and physiological development of the child. However, whether cannabis use relates to altered human brain development prior to birth, and specifically, whether maternal prenatal cannabis use relates to connectivity of fetal functional brain systems, remains an open question. The major objective of this study was to identify whether maternal prenatal cannabis exposure (PCE) is associated with variation in human brain hippocampal functional connectivity prior to birth. Prenatal drug toxicology and fetal fMRI data were available in a sample of 115 fetuses [43 % female; mean age 32.2 weeks ( SD = 4.3)]. Voxelwise hippocampal connectivity analysis in a subset of age and sex-matched fetuses revealed that PCE was associated with alterations in fetal dorsolateral, medial and superior frontal, insula, anterior temporal, and posterior cingulate connectivity. Classification of group differences by age 5 outcomes suggest that compared to the non-PCE group, the PCE group is more likely to have increased connectivity to regions associated with less favorable outcomes and to have decreased connectivity to regions associated with more favorable outcomes. This is preliminary evidence that altered fetal neural connectome may contribute to neurobehavioral vulnerability observed in children exposed to cannabis in utero .

show abstract

Maternal childhood adversity and inflammation during pregnancy: Interactions with diet quality and depressive symptoms

Cited by 19 publications

References 74 publications

Influences of adversity across the lifespan on respiratory sinus arrhythmia during pregnancy

Influences of adversity across the lifespan on respiratory sinus arrhythmia during pregnancy

Biological embedding vs. embodiment of social experiences: How these two concepts form distinct thought styles around the social production of health inequalities

Miswiring the brain: Human prenatal Δ9-tetrahydrocannabinol use associated with altered fetal hippocampal brain network connectivity

Contact Info

Product

Resources

About