“…A clear knowledge of cerebrospinal fluid (CSF) pathways is still lacking [1,2]. The results of the article, entitled ''Two cases of persistent falcine and occipital sinuses" by Inui et al [3] and recently published in Brain & Development (2020), indicate some important clues in better understanding of the pathophysiology of the disorders which can be associated with disturbances of the CSF circulation. As the authors stated, an acquired Chiari Ⅰ malformation can be associated with a pressure gradient across the cranial and spinal compartments.…”