Estudio epidemiológico de Haemophilus influenzae causante de enfermedad invasiva y no invasiva en Paraguay (1999-2017)

Invasive Haemophilus influenzae Infections after 3 Decades of Hib Protein Conjugate Vaccine Use

“…The incidence rates of Hia meningitis increased 8-fold, from 0.02/100,000 person-years in 1996 to 0.16 cases/ 100,000 person-years in 2000 (98). In Paraguay, invasive Hib infections in children ,5 years of age declined following the introduction of Hib vaccine but was associated with an increase in invasive NTHi infections in older children and adults (99).…”