32. The formation of organo-metalloidal compounds by microorganisms. Part I. Trimethylarsine and dimethylethylarsine

Challenger, Frederick; Higginbottom, Constance; Ellis, Louis

doi:10.1039/jr9330000095

Cited by 73 publications

(39 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…When the reaction between Gosio gas and HgCl 2 was reexamined by Challenger and his associates, two crystalline mercuric chloride precipitates were obtained, depending on the time of aspiration (40,46). These compounds were the di-and mono-mercurichloride of trimethylarsine, (CH 3 ) 3 As · 2HgCl 2 and (CH 3 ) 3 As · HgCl 2 , respectively.…”

Section: Gosio Gas Is Trimethylarsinementioning

confidence: 99%

Microbial Methylation of Metalloids: Arsenic, Antimony, and Bismuth

Bentley

Chasteen

2002

Microbiol Mol Biol Rev

514

316

View full text Add to dashboard Cite

A significant 19th century public health problem was that the inhabitants of many houses containing wallpaper decorated with green arsenical pigments experienced illness and death. The problem was caused by certain fungi that grew in the presence of inorganic arsenic to form a toxic, garlic-odored gas. The garlic odor was actually put to use in a very delicate microbiological test for arsenic. In 1933, the gas was shown to be trimethylarsine. It was not until 1971 that arsenic methylation by bacteria was demonstrated. Further research in biomethylation has been facilitated by the development of delicate techniques for the determination of arsenic species. As described in this review, many microorganisms (bacteria, fungi, and yeasts) and animals are now known to biomethylate arsenic, forming both volatile (e.g., methylarsines) and nonvolatile (e.g., methylarsonic acid and dimethylarsinic acid) compounds. The enzymatic mechanisms for this biomethylation are discussed. The microbial conversion of sodium arsenate to trimethylarsine proceeds by alternate reduction and methylation steps, with S-adenosylmethionine as the usual methyl donor. Thiols have important roles in the reductions. In anaerobic bacteria, methylcobalamin may be the donor. The other metalloid elements of the periodic table group 15, antimony and bismuth, also undergo biomethylation to some extent. Trimethylstibine formation by microorganisms is now well established, but this process apparently does not occur in animals. Formation of trimethylbismuth by microorganisms has been reported in a few cases. Microbial methylation plays important roles in the biogeochemical cycling of these metalloid elements and possibly in their detoxification. The wheel has come full circle, and public health considerations are again important

show abstract

Section: Gosio Gas Is Trimethylarsinementioning

confidence: 99%

Microbial Methylation of Metalloids: Arsenic, Antimony, and Bismuth

Bentley

Chasteen

2002

Microbiol Mol Biol Rev

514

316

View full text Add to dashboard Cite

show abstract

“…Gosio originally presumed that the garlic-odored gas was Me 2 AsH (Bentley and Chasteen, 2002). Until early 1930s, Challenger and his colleagues demonstrated that "Gosio gas" was TMAs, not Me 2 AsH (Challenger et al, 1933). Two strains of fungi isolated from sewage, belonging to Gliocladium roseum and a Penicillium sp., were shown to produce TMAs from substrates methylarsonate and dimethylarsinate under proper conditions.…”

Section: Microorganisms Capable Of Volatilizing As 21 Fungimentioning

confidence: 99%

A review on completing arsenic biogeochemical cycle: Microbial volatilization of arsines in environment

Wang¹,

Sun²,

Jia³

et al. 2014

Journal of Environmental Sciences

144

View full text Add to dashboard Cite

a b s t r a c t Arsenic (As) is ubiquitous in the environment in the carcinogenic inorganic forms, posing risks to human health in many parts of the world. Many microorganisms have evolved a series of mechanisms to cope with inorganic arsenic in their growth media such as transforming As compounds into volatile derivatives. Bio-volatilization of As has been suggested to play an important role in global As biogeochemical cycling, and can also be explored as a potential method for arsenic bioremediation. This review aims to provide an overview of the quality and quantity of As volatilization by fungi, bacteria, microalga and protozoans. Arsenic bio-volatilization is influenced by both biotic and abiotic factors that can be manipulated/elucidated for the purpose of As bioremediation. Since As biovolatilization is a resurgent topic for both biogeochemistry and environmental health, our review serves as a concept paper for future research directions.

show abstract

“…Trimethylarsine [(CH 3 ) 3 As] was identified by Challenger and co-workers 1,2 as a product of mould metabolism. Subsequent studies demonstrated that the ability to produce trimethylarsine was widespread amongst yeasts and fungi and that biological methylation of arsenic was a general phenomenon.…”

Section: Introductionmentioning

confidence: 99%

Photochemical alkylation of inorganic arsenic : Part 1. Identification of volatile arsenic species

Guo

Sturgeon

Mester

et al. 2005

J. Anal. At. Spectrom.

View full text Add to dashboard Cite

Access and use of this website and the material on it are subject to the Terms and Conditions set forth at Photochemical alkylation of inorganic arsenic. Part 1. Identification of volatile arsenic species Guo, X. M.; Sturgeon, R.; Mester, Z.; Gardner, G. J.http://nparc.cisti-icist.nrc-cnrc.gc.ca/npsi/jsp/nparc_cp.jsp?lang=fr L'accès à ce site Web et l'utilisation de son contenu sont assujettis aux conditions présentées dans le site LISEZ CES CONDITIONS ATTENTIVEMENT AVANT D'UTILISER CE SITE WEB. NRC Publications Record / Notice d'Archives des publications de CNRC:http://nparc.cisti-icist.nrc-cnrc.gc.ca/npsi/ctrl?action=rtdoc&an=8898768&lang=en http://nparc.cisti-icist.nrc-cnrc.gc.ca/npsi/ctrl?action=rtdoc&an=8898768&lang=fr READ THESE TERMS AND CONDITIONS CAREFULLY BEFORE USING THIS WEBSITE.http://nparc.cisti-icist.nrc-cnrc.gc.ca/npsi/jsp/nparc_cp.jsp?lang=en Vous avez des questions? Nous pouvons vous aider. Pour communiquer directement avec un auteur, consultez la première page de la revue dans laquelle son article a été publié afin de trouver ses coordonnées. Si vous n'arrivez pas à les repérer, communiquez avec nous à PublicationsArchive-ArchivesPublications@nrc-cnrc.gc.ca. Questions? Contact the NRC Publications Archive team atPublicationsArchive-ArchivesPublications@nrc-cnrc.gc.ca. If you wish to email the authors directly, please see the first page of the publication for their contact information. NRC Publications Archive Archives des publications du CNRCThis publication could be one of several versions: author's original, accepted manuscript or the publisher's version. / La version de cette publication peut être l'une des suivantes : la version prépublication de l'auteur, la version acceptée du manuscrit ou la version de l'éditeur. For the publisher's version, please access the DOI link below./ Pour consulter la version de l'éditeur, utilisez le lien DOI ci-dessous.http://doi.org/10.1039/b503661eJournal of Analytical Atomic Spectrometry, 20, 8, pp. 702-708, 2005 Photochemical alkylation of inorganic arsenic Volatile arsenic species generated by UV irradiation of aqueous solutions of arsenite in low molecular weight (LMW) carboxylic acid media (formic, acetic, propionic and butyric) were identified using ICP-TOF-MS and GC-MS. Cryogenic trapping-GC-MS reveals that inorganic arsenite can be alkylated to yield AsH 3 in the presence of formic acid, trimethylarsine in acetic acid, triethylarsine in propionic acid and tripropylarsine in butyric acid solutions. Mixed ligand arsenic species such as methylarsine, dimethylarsine, dimethylethylarsine and diethylmethylarsine are also formed when a mixture of acids is used. Using 0.05 mg l À1 As(III) as the test solution in 3.1 M acetic acid, a methylation efficiency of approximately 75% was achieved.

show abstract

32. The formation of organo-metalloidal compounds by microorganisms. Part I. Trimethylarsine and dimethylethylarsine

Cited by 73 publications

References 0 publications

Microbial Methylation of Metalloids: Arsenic, Antimony, and Bismuth

Microbial Methylation of Metalloids: Arsenic, Antimony, and Bismuth

A review on completing arsenic biogeochemical cycle: Microbial volatilization of arsines in environment

Photochemical alkylation of inorganic arsenic : Part 1. Identification of volatile arsenic species

Contact Info

Product

Resources

About