31P-NMR and Differential Scanning Calorimetry Studies for Determining Vesicle’s Drug Physical State and Fraction in Alendronate Liposomes

Afergan, Eyal; Najajreh, Yousef; Gutman, Dikla; Epstein, H.; Elmalak, Omar; Golomb, Gershon

doi:10.4172/1948-593x.1000035

Cited by 8 publications

(6 citation statements)

References 12 publications

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“…Enhanced delivery of encapsulated DNA by membrane fusion, protection of nucleic acids from nuclease activity, targeting to specific cells, delivery into a variety of cell types besides protoplasts by entry through plasmodesmata [50] .In Liposome based gene therapy there is no toxicity potential in humans and plants [51].Our results should stimulate efforts to develop plant-based technologies for the removal of pollutants from contaminated environments [52]. Specific molecular changes have been suggested to be the reasons for the growth of gene therapies [53] a liposomal delivery system requires a complete understanding of the physicochemical characteristics of the drugliposome system [54].…”

Section: Liposome Gene Transfermentioning

confidence: 99%

“…The liposome-based gene transfer strategy is one of the most studied Nonviral gene delivery strategies [47].A liposomal delivery system requires a complete understanding of the physicochemical characteristics of the drug-liposome system [48]. Many bacteria can control plant diseases by altering molecular processes leading to the production of pathogenicity and/or virulence factors by the pathogen [49].…”

Section: Liposome Gene Transfermentioning

confidence: 99%

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Nanotechnology in Agriculture

Srilatha¹

2011

J Nanomed Nanotechnol

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Agriculture is an area where new technologies are often applied to improve the yield of crops. Nano agriculture involves the employment of Nano particles in agriculture these particles will impart some beneficial effects to crops. The emergence of nanotechnology and the development of new Nanodevices and Nanomaterials open up potential novel applications in agriculture and biotechnology. Nanoparticles are materials that are small enough to fall within the nanometric range, with at least one of their dimensions being less than a few hundred nanometers. These materials would release pesticides or fertilizers at a specific time and targeted location. Nanoparticles tagged to agrochemicals or other substances could reduce the damage to other plant tissues and the amount of chemicals released into the environment.

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Section: Liposome Gene Transfermentioning

confidence: 99%

Section: Liposome Gene Transfermentioning

confidence: 99%

Nanotechnology in Agriculture

Srilatha¹

2011

J Nanomed Nanotechnol

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“…The membranes of liposomes are usually derived from phospholipids with mixed lipid chains and head groups or pure synthetic lipids with defined acyl chains and head groups. The drugs can be either entrapped at bilayer interface, in aqueous volume or in phospholipids bilayer [27]. Liposomes which are formed from phospholipids are mostly used to modify the pharmacokinetic profile of drugs, enzymes etc.…”

Section: Site Directed Drug Carrying Vehicles / Drug Carriersmentioning

confidence: 99%

An Imperative Note on Novel Drug Delivery Systems

Bheemidi¹,

Tiruckovela²,

Varanasi³

2011

J Nanomed Nanotechnol

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A new era of science and technology has evolved in pharmaceutical research focussed at development of different novel drug delivery systems. The evolution of an existing drug from its traditional form to a novel delivery system may considerably improve its performance in aspects of efficacy, safety and patient compliance. So the method of administrating a drug can also have significant effect in its efficacy. In recent years the considerable advances in drug delivery systems have enabled more effective routes of administration. This review highlights the different novel drug delivery system, drug carriers and their potential to resolve the current challenges faced by biotechnology and pharmaceutical Industries.

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“…GDEPT, also known as suicide gene therapy is a similar targeted technique where the gene for foreign enzyme is delivered (mostly by Liposomal or polymer mediated gene delivery) [29][30][31][32][33][34][35] to the tumor cell which further activates the non toxic prodrug at the site of action [35]. Here the genes are controlled at transcription site by using specific promoter that becomes active in target cells transcribing to mRNA which further translates in to protein.…”

Section: Gene-directed Enzyme Prodrug Therapy (Gdept)mentioning

confidence: 99%

Cutting Edge Approach on Prodrug: Contrivance for Target Drug Delivery

Varsha¹,

Rao²,

Rao³

2011

JBB

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Drug administration procedures are very much vital and are considered to be the prime-most criteria during the drug design and its appliance. Scrutinizing this, drugs are designed in such a way, bringing some change in their persona like bioavailability and bioequivalence. One such approach called prodrug, first started in 1950's is still a fertile area of research because of it's insist persona. Prodrugs are the shrouded drugs which are one or two chemical or enzymatic steps away from the active parent drug. Present review delineates about the prodrug action, types of prodrugs, new prodrug therapies, nanotech allied prodrugs.

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31P-NMR and Differential Scanning Calorimetry Studies for Determining Vesicle’s Drug Physical State and Fraction in Alendronate Liposomes

Cited by 8 publications

References 12 publications

Nanotechnology in Agriculture

Nanotechnology in Agriculture

An Imperative Note on Novel Drug Delivery Systems

Cutting Edge Approach on Prodrug: Contrivance for Target Drug Delivery

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