31P kernspinspektroskopie der magenwand nach proximaler selektiver vagotomie

Abstract

The phosphate metabolism of the gastric wall after proximal selective vagotomy (PSV) was investigated by means of 31P-NMR spectroscopy. The destruction of metabolism has been found just after PSV resulting in a significant decrease of adenosine diphosphates and adenosine triphosphates. 4 and 7 days after PSV the progress of metabolism regeneration was detected, nevertheless with the retardation of high energy phosphates ischemic degradation. The results indicate not only a hydrochloric acid activity reduction but diminution of gastric mucosa protective factors, too. In experimental gastric ulcers no energy phosphates have been found suggesting a mucosa cells necrobiosis.