311 Magnesium May Cross The Intact Blood Brain Barrier in Humans

Amadeu, E.; Lopes, Edgar; Barbot, J.; Meireles, Alexandra; Amorim, Pedro

doi:10.1097/00008506-199910000-00071

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2006

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“…Clearly magnesium also works in the brain because in patients with toxemia of pregnancy, magnesium increases seizure threshold (12). In addition, in patients who were scheduled for a spinal anesthetic, patients were randomly assigned to receive either a bolus intravenous infusion of MgSO 4 or saline solution, 30 minutes before undergoing the spinal (1,5,6,10). Magnesium levels from serum were measured before the infusions and from serum and CSF after the infusion.…”

Section: Discussionmentioning

confidence: 99%