306: The Impact of Sleeve Gastrectomy on the Gastric Conduction System Measured by Body Surface Gastric Mapping

Robertson, Sam; Carson, Daniel; Wang, Tim H.; Wang, Jim Hsu‐Shun; Calder, Stefan; Andrews, Christopher N.; Varghese, Chris; Sebaratnam, Gabrielle; Woodhead, Jonathan S.; Gharibans, Armen A.; Windsor, John A.; O’Grady, Gregory

doi:10.1016/s0016-5085(22)63859-9

Cited by 2 publications

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“…Contrary to our findings, Robertson et al [ 23 ] compared EGG findings in sleeve gastrectomy patients (at only three months after surgery) with matched healthy controls (i.e., a case-control pattern) and found that gastric rhythm was significantly lower in patients compared to controls and GMA amplitude was also lower in sleeve gastrectomy patients. This difference between our results and those of Robertson et al resulted from using different devices and different study designs.…”

Section: Discussioncontrasting

confidence: 99%

Gastric Myoelectric Activity and Body Composition Changes during Weight Loss via Sleeve Gastrectomy and Lifestyle Modification: Prospective Cohort Study

et al. 2023

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The capability of bariatric surgery (BS) and lifestyle intervention (LSI) in ameliorating obesity-associated altered gastric myoelectric activity (GMA) in relation to body composition is underinvestigated. This work studied GMA during weight loss via sleeve gastrectomy and multimodal lifestyle intervention. Seventy-nine participants with morbid obesity were assigned into three groups: bariatric surgery (BS group, n = 27), in which laparoscopic sleeve gastrectomy was performed; lifestyle intervention (LS group, n = 22), in which a calorie-deficit balanced diet with gradual physical activity and personalized behavioral modification were carried out; and waitlist control (C group, n = 30). For all participants, multichannel electrogastrography (EGG) with water-load testing and bioelectric impedance body composition analysis were done at baseline, after three months, and at six months. In the BS group, the water-load volume was decreased but without improvement in the bradygastria. In the LS group, preprandial bradygastria were reduced and some postprandial normogastria were increased throughout the study period. Except for fat-free mass and total body water, the parameters of body composition changes were superior in the BS group. In the LS group, the amount of fat-mass loss was negatively correlated with bradygastria times and positively correlated with preprandial and the early postprandial average dominant frequency (ADF). In addition, in the BS group, fat-mass loss was positively correlated with the ADF at late postprandial times. In conclusion, compared to BS, LS produced moderate normalization of GMA with the preservation of fat-free mass. The GMA changes were significantly associated with the amount of fat loss, regardless of the method of obesity management.

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Section: Discussioncontrasting

confidence: 99%

Gastric Myoelectric Activity and Body Composition Changes during Weight Loss via Sleeve Gastrectomy and Lifestyle Modification: Prospective Cohort Study

et al. 2023

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“…30,[62][63][64] Recently, Robertson et al studied recovery of the gastric conduction system following LSG patients in 21 patients with good functional outcomes, using the new technique of body surface gastric mapping (ie, HR-EGG). 65 Preliminary data revealed that mean gastric slow wave frequencies dropped into the bradygastric range after LSG (mean 2.3 cpm), again with reduced stability, but with propagation generally remaining antegrade.…”

Section: Sleeve Gastrectomy and Resection Of Greater Curve And Primar...mentioning

confidence: 94%

The Impact and Clinical Implications of Gastric Surgery on the Gastric Conduction System

Carson

Robertson

Wang

et al. 2022

Foregut: The Journal of the American Foregut Society

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Chronic symptoms of gastric dysfunction are common following gastric surgery, but the mechanisms underlying these have remained poorly understood. Disturbances of foregut motility are suspected to play a central role, however knowledge of how these abnormalities manifest and relate to symptoms requires elucidation. Emerging data suggests that abnormalities of the gastric conduction system are a common consequence of gastric surgery and may contribute to dysmotility and post-operative symptoms. This review provides a primer on the gastric conduction system. The normal physiology of the gastric conduction system and factors that influence resilience to surgery are outlined, together with focused discussion on three surgical procedures that impact post-operative gastric dysfunction: resection of the gastric pacemaker, resection or bypass of the pylorus, and vagotomy. The mechanistic pathways that underpin the clinical effects of these procedures are discussed. Future horizons are also evaluated, including newly established body surface gastric mapping techniques that provide a non-invasive method to detect changes in the gastric conduction system and relate these to symptoms in postoperative patients, with the goal of developing targeted interventions for prevention and therapy.

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306: The Impact of Sleeve Gastrectomy on the Gastric Conduction System Measured by Body Surface Gastric Mapping

Cited by 2 publications

References 0 publications

Gastric Myoelectric Activity and Body Composition Changes during Weight Loss via Sleeve Gastrectomy and Lifestyle Modification: Prospective Cohort Study

Gastric Myoelectric Activity and Body Composition Changes during Weight Loss via Sleeve Gastrectomy and Lifestyle Modification: Prospective Cohort Study

The Impact and Clinical Implications of Gastric Surgery on the Gastric Conduction System

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