The impact of analytical variation of hemoglobin measurement on blood donors' hemoglobin and deferral rates

Castrén, Johanna; Arvas, Mikko; Valkeajärvi, Anne; Korkalainen, Piia; Syrjälä, Martti

doi:10.1111/trf.14825

Cited by 1 publication

(1 citation statement)

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“…For this study, it should be noted that the HemoCue is calibrated for use in normobaric air, and there was no prior experience of its use in a hyperbaric heliox atmosphere. We noticed that the readings after blow-down appeared higher than those done before the divers entered the hyperbaric chambers, but the difference was within the range expected for this Hb device (Rappaport et al, 2017; Castren et al, 2018).…”

Section: Discussionsupporting

confidence: 53%

Hemoglobin During and Following a 4-Week Commercial Saturation Dive to 200 m

et al. 2019

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Commercial saturation divers must acclimatize to hyperbaric hyperoxia in their work environment, and subsequently readjust to breathing normal air when their period in saturation is over. In this study, we measured hemoglobin (Hb) during and following 4 weeks of heliox saturation diving in order to monitor anemia development and the time for Hb to recover post-saturation. Male commercial saturation divers reported their capillary blood Hb daily, before, and during 28 days of heliox saturation to a working depth of circa 200 m (n = 11), and for 12 days at surface post-saturation (n = 9–7), using HemoCue 201+ Hb devices. Hb remained in normal range during the bottom phase, but fell during the decompression; reaching levels of mild anemia (≤13.6 g/dl) the day after the divers’ return to the surface. Hb was significantly lower than the pre-saturation baseline (14.7 ± 1.1 g/dl) on the fifth day post-saturation (12.8 ± 1.8 g/dl, p = 0.028), before reverting to normal after 6–7 days. At the end of the 12-day post-saturation period, Hb was not statistically different from the pre-saturation baseline. The observed Hb changes, although significant, were modest. While we cannot rule out effect of other factors, the presence of mild anemia may partially explain the transient fatigue that commercial saturation divers experience post-saturation.

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Section: Discussionsupporting

confidence: 53%