Advanced Stage Breast Sarcoma Treatment in a Third World Country Public Hospital

Faria, Amanda Lino de; Garcia, Cinthia Moreno; Rodrigues, Gabriela de Andrade; Santos, Lais Helena Dumbra Toloni dos; Uyeda, Gabriela B. K.; Elias, Simone; Sartori, Marair Grácio Ferreira; Nazário, Afonso Celso Pinto; Facina, Gil

doi:10.1155/2018/4985012

Cited by 2 publications

(1 citation statement)

References 8 publications

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“…Lim et al reported similar five-year overall and disease-free survival rates for patients with breast sarcomas and patients with malignant phyllodes tumors (86.5% versus 78.5% p=0.792, respectively, and 59.1% versus 57.4% p=0.816, respectively) [2]. The disease-free survival rate varies between 33% and 52% [15]. A meta-analysis of 54 studies including a total of 9234 reported a local recurrence rate of 18% for malignant phyllodes tumors.…”

Section: Discussionmentioning

confidence: 89%

Malignant Mesenchymal and Fibroepithelial Breast Tumors - Presentation of Three Cases

2019

IJCRT

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Introduction: Malignant mesenchymal breast tumors, as is the case also with malignant phyllodes tumors, are rare malignancies that share several clinical and pathological characteristics. They are often locally aggressive and have a high potential for distant metastasis. This paper reports two cases of malignant phyllodes tumors and one case of breast sarcoma managed by our breast surgery team. One of the malignant phyllodes tumors showed rapid progression with early multiple visceral involvement and death. Discussion: Presentation of an updated review of the literature covering clinical, pathological, radiological and therapeutic considerations related to breast sarcomas and malignant phyllodes tumors. Conclusion: Breast sarcomas and malignant phyllodes tumors are rare breast malignancies that share more similarities than differences and require a multidisciplinary approach to management.

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Section: Discussionmentioning

confidence: 89%

Malignant Mesenchymal and Fibroepithelial Breast Tumors - Presentation of Three Cases

2019

IJCRT

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Primary stromal sarcoma of breast: A case report and literature review

Al-Wiswasy

Al-Balas

Al-Saffar

et al. 2021

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INTRODUCTION: Primary breast sarcoma (PBS) was first described in 1887 as a rare heterogeneous neoplasm arising from the mesenchymal tissue of the mammary gland accounting for less than 5% of all body soft-tissue sarcomas and less than 0.1% of all malignant tumors of the breast. CASE PRESENTATION: A 31-year old lady presented with left breast mass which she felt four years before during which the mass increased in size from 1 to 6 cm in the largest diameter, diagnosed clinically as a benign fibroadenoma without any further cytological or histopathological confirmation. Histopathological examination of the excised breast mass reveals undifferentiated, primary stromal sarcoma of the breast (PSSB), which was followed by mastectomy three weeks later with reconstructive breast surgery with a total duration of follow-up of 3 years thereafter. This is the first case of PSSB reported in Jordan. DISCUSSION/CONCLUSION: PSSB is the generic term given to malignant breast tumors thought to arise from the specialized mesenchymal stroma of the breast but lacking an epithelial component with a phylloides pattern. PSSB is difficult to diagnose preoperatively due to its rarity and inadequate imaging methods to establish an exact diagnosis. The histology of the patient mass may be the leading factor for the management of these tumors. Even in very young patients, a progressively growing breast mass should alert the clinician to investigate for malignancy and verify the results by biopsy. Surgery with adequate resection margins represents the only potentially curative modality with prognostic significance. Adjuvant chemotherapy and radiotherapy are not very beneficial. The prognosis is dismal for patients with lymph node involvement and the size of the tumor has a lesser bearing on the outcome.

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Advanced Stage Breast Sarcoma Treatment in a Third World Country Public Hospital

Cited by 2 publications

References 8 publications

Malignant Mesenchymal and Fibroepithelial Breast Tumors - Presentation of Three Cases

Malignant Mesenchymal and Fibroepithelial Breast Tumors - Presentation of Three Cases

Primary stromal sarcoma of breast: A case report and literature review

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