Bullous sweet syndrome healing with prominent secondary anetoderma

Abstract

A 15-month-old boy presented with 1-4 cm, pink edematous plaques with overlying round erosions and hemorrhagic bullae in the setting of a gastrointestinal illness and was ultimately diagnosed with bullous-type Sweet syndrome. Despite appropriate treatment with oral steroids, the patient's cutaneous lesions healed with secondary anetoderma. This case should prompt practitioners to be aware of bullous-type Sweet syndrome and the possibility of lesions healing with postinflammatory scarring.

Histiocytoid Sweet syndrome recalcitrant to prednisone causing severe scarring

“…Mild scarring has been reported rarely in classic Sweet syndrome 9 , 10 . Cutis laxa and anetoderma have also been described 11 , 12 . This is the first patient, to our knowledge, reported to have severe hypertrophic scar formation caused by histiocytoid Sweet syndrome.…”

Anetoderma Schweninger-Buzzi: Two Case Reports

“…Primary anetoderma can be a precursor of autoimmune disorders and a marker for prothrombotic conditions like anti-phospholipid syndrome [7], [9], [10]. Secondary anetoderma has been reported after granuloma annulare [11], secondary syphilis [12], pilomatricoma [13], and bullous Sweet syndrome [14]. Acquired anetoderma following folliculitis is known in patients with Down syndrome [15].…”