Pilot study on a new concept of documenting the clinical relevance of patch test results in contact dermatitis patients

Uter, Wolfgang; Bauer, Andrea; Bensefa‐Colas, Lynda; Brans, Richard; Crépy, Marie‐Noëlle; Giménez‐Arnau, Ana; Filon, Francesca Larese; Hadžavdić, Suzana Ljubojević; Pesonen, Maria; Schuttelaar, Marie L A; Wilkinson, S. M.

doi:10.1111/cod.13097

Cited by 8 publications

(4 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Occupational physicians in insurance companies check the medical certificates and control whether the requirements for an OSD are fulfilled. Only recently have patch test databases started to resolve the problem of recording relevance data of individual patch test reactions 7 …”

Section: Discussionsupporting

confidence: 79%

12‐year data on skin diseases in the Finnish Register of Occupational Diseases II: Risk occupations with special reference to allergic contact dermatitis

2020

Self Cite

View full text Add to dashboard Cite

Background: Detailed epidemiological studies on occupational skin diseases (OSDs) are scarce.Objectives: To analyze risk occupations for OSDs in the Finnish Register of Occupational Diseases (FROD). Methods:We retrieved numbers of OSD cases (excluding skin infections) for different occupations from the FROD in 2005-2016. In the FROD, Finnish ISCO-08-based classification of occupations was used since 2011, and the preceding ISCO-88-based version until 2010. We combined cases from the earlier and the later period using conversion tables provided by Statistics Finland. We included occupations with at least five cases and analyzed them in detail. We calculated incidence rates for OSDs and separately for allergic contact dermatitis (ACD) in different risk occupations using national labor force statistics. We also studied causes of ACD in these occupations.Results: Risk occupations with the largest number of OSD cases included farmers, hairdressers, assistant nurses, cooks, cleaners, machinists, and nurses. Occupations with the highest incidences of OSDs comprised spray painters (23.8/10 000 person years), bakers (20.4), and dental technicians (19.0). Epoxy compounds and acrylates were prominent causes of ACD in occupations with the highest incidences of ACD.

show abstract

Section: Discussionsupporting

confidence: 79%

12‐year data on skin diseases in the Finnish Register of Occupational Diseases II: Risk occupations with special reference to allergic contact dermatitis

2020

Self Cite

View full text Add to dashboard Cite

show abstract

“…We are hopeful that a new concept regarding the final evaluation of patients who undergo patch testing and the documentation of clinical relevance of allergic patch-test reactions that has recently been suggested will be adopted at some stage, thereby enabling better individual documentation and detailed epidemiological analysis. 38…”

Section: Discussionmentioning

confidence: 99%

“…Another limitation of this study is the inability to link an allergic reaction to information that is collected on a case‐wise basis (and not allergen‐wise basis), such as the anatomical site of dermatitis, in the documentation system currently used. We are hopeful that a new concept regarding the final evaluation of patients who undergo patch testing and the documentation of clinical relevance of allergic patch‐test reactions that has recently been suggested will be adopted at some stage, thereby enabling better individual documentation and detailed epidemiological analysis 38…”

Section: Discussionmentioning

confidence: 99%

Trends and current spectrum of contact allergy in Central Europe: results of the Information Network of Departments of Dermatology (IVDK) 2007–2018*

et al. 2020

Self Cite

View full text Add to dashboard Cite

Summary Background Changing patterns of exposure lead to changes in the spectrum of contact allergy in the general population and in patients patch tested for suspected contact allergy. The main contact allergens (haptens) are assembled in the so‐called ‘baseline series’. Objectives To present the current spectrum of contact allergy to baseline series allergens, and its temporal development over the last 12 years, based on data collected by the 56 active departments of the trinational Information Network of Departments of Dermatology (IVDK). Methods Patch‐test data, along with core demographic and clinical information, subdivided into 4‐year periods for all patients patch tested with the baseline series in the IVDK, were analysed descriptively. Moreover, log‐binomial regression analysis addressed temporal trends of specific contact allergies, adjusted for potentially confounding factors. Results Among the 125 436 patients tested with the German baseline series, the most common allergens were nickel (14·7%), fragrance mix I (8·1%), Myroxylon pereirae resin (7·5%) and cobalt (5·2%), with no conclusive trend. The rise and fall of contact allergy to methylchloroisothiazolinone/methylisothiazolinone (MI), following (self‐) regulation in the European Union, reflected the MI contact allergy epidemic. Propolis showed a marked upward trend with a prevalence of 3·94% during the period 2015–2018. Conclusions Decreases in sensitization prevalence likely reflect reduced exposure, with some lag, as seen with hydroxyisohexyl 3‐cyclohexene carboxaldehyde. If no (sufficient) decrease can be observed despite interventions, such as for nickel and chromium, affected subgroups should be identified and their causative exposures explored. Finally, increases such as that observed with propolis, certainly warrant targeted investigation of the exposures driving sensitization, and possibly intervention. What is already known about this topic? Contact allergy is prevalent in the general population. Surveillance based on clinical data offers timely information on trends concerning certain allergens or subgroups at risk. What does this study add? This analysis provides an update of the current contact allergy prevalence in Central Europe, including time trends. This study describes the demographic and clinical profile of patients tested from 2007 to 2018. This research identifies contact allergens that require (further) preventive efforts. Linked Comment: Schuttelaar. Br J Dermatol 2020; 183:800–801.

show abstract

“…Another limitation is that the relevance of individual positive patch test reactions was not taken into account, as it was not registered systematically in all centres. To overcome this problem in the future, an “extended ESSCA” database has been developed as a concept, providing the possibility of very precisely linking positive patch test reactions to body sites, along with current and past relevance for the dermatitis that the patient presented with . Furthermore, a small subgroup was not included in the analyses.…”

Section: Discussionmentioning

confidence: 99%

European Surveillance System on Contact Allergies (ESSCA): Contact allergies in relation to body sites in patients with allergic contact dermatitis

et al. 2019

Self Cite

View full text Add to dashboard Cite

Background Analyses of the European Surveillance System on Contact Allergies (ESSCA) database have focused primarily on the prevalence of contact allergies to the European baseline series, both overall and in subgroups of patients. However, affected body sites have hitherto not been addressed. Objective To determine the prevalence of contact allergies for distinct body sites in patients with allergic contact dermatitis (ACD). Methods Analysis of data collected by the ESSCA ( www.essca‐dc.org ) in consecutively patch tested patients, from 2009 to 2014, in eight European countries was performed. Cases were selected on the basis of the presence of minimally one positive patch test reaction to the baseline series, and a final diagnosis of ACD attributed to only one body site. Results Six thousand two hundred and fifty‐five cases were analysed. The head and hand were the most common single sites that ACD was attributed to. Differences between countries were seen for several body sites. Nickel, fragrance mix I, cobalt and methylchloroisothiazolinone/methylisothiazolinone were the most frequent allergens reported for various body sites. Conclusions Distinct allergen patterns per body site were observed. However, contact allergies were probably not always relevant for the dermatitis that patients presented with. The possibility of linking positive patch test reactions to relevance, along with affected body sites, should be a useful addition to patch test documentation systems.

show abstract

Pilot study on a new concept of documenting the clinical relevance of patch test results in contact dermatitis patients

Cited by 8 publications

References 13 publications

12‐year data on skin diseases in the Finnish Register of Occupational Diseases II: Risk occupations with special reference to allergic contact dermatitis

12‐year data on skin diseases in the Finnish Register of Occupational Diseases II: Risk occupations with special reference to allergic contact dermatitis

Trends and current spectrum of contact allergy in Central Europe: results of the Information Network of Departments of Dermatology (IVDK) 2007–2018*

European Surveillance System on Contact Allergies (ESSCA): Contact allergies in relation to body sites in patients with allergic contact dermatitis

Contact Info

Product

Resources

About