Tactile learning transfer from the hand to the face but not to the forearm implies a special hand-face relationship

Muret, Dollyane; Dinse, Hubert R.

doi:10.1038/s41598-018-30183-5

Cited by 11 publications

(12 citation statements)

References 51 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This has already been indicated by studies on M1 neurodegeneration where disease spread markedly differs depending on which body part is first affected [38]. Other than previously described for the primary somatosensory cortex of younger adults [39], [40], our findings indicate that plasticity and disease mechanisms in M1 may not transfer to other body parts.…”

Section: Discussionsupporting

confidence: 72%

Layer-Specific Vulnerability is a Mechanism of Topographic Map Aging

Northall

Doehler

Weber

et al. 2022

Preprint

View full text Add to dashboard Cite

Age-related cortical plasticity reveals insights into the mechanisms underlying the stability and flexibility of neuronal circuits. Classical parcellation has long demonstrated the importance of microstructural features yet 3D approaches have rarely been applied to human brain organization in-vivo. We acquired functional and structural 7T-MRI and behavioral data of living younger and older adults to investigate human primary motor cortex (M1) aging, employing 3D parcellation techniques. We identify distinct cortical fields in M1 based on quantitative tissue contrast, which are, along with the myelin-poor borders between them, stable with age. We also show age-related iron accumulation, particularly in the output layer 5b and the lower limb field. Our data offers a new model of human M1 with distinct cortical fields, a mechanistic explanation for the stability of topographic organization in the context of aging and plasticity, and highlights the specific vulnerability of output signal flows to cortical plasticity.

show abstract

Section: Discussionsupporting

confidence: 72%

Layer-Specific Vulnerability is a Mechanism of Topographic Map Aging

Northall

Doehler

Weber

et al. 2022

Preprint

View full text Add to dashboard Cite

show abstract

“…Interestingly, in physiological state, a study of fMRI showed speci c correlation between LI4 and orofacial muscles, activating a wide range of overlapping and adjacent brain regions [44]. Furthermore, somatosensory stimulation can induce plasticity changes across hand and face representation, both in primary sensory cortex [45,46] and motor cortex [47]. These ndings provide evidences for explaining the relation between hand and face.…”

Section: Discussionmentioning

confidence: 99%

Different intensities of electroacupuncture for peripheral facial paralysis sequelae: study protocol for a randomized placebo-controlled trial

Huang

Wan

Chen

et al. 2023

Preprint

View full text Add to dashboard Cite

Background: Peripheral facial paralysis (PFP) is a common neurological disease. Many patients have obtained benefits from the treatment of PFP sequelae by electroacupuncture (EA). However, there is limited evidence for the efficacy between different EA intensities. Hence, this study presents a new approach based on different EA intensities to verify the effectiveness by combining neurological function scales in the sequelae of PFP. Methods: In this placebo-controlled trial, a total of 66 patients with peripheral facial paralysis sequelae will be randomly divided into sensory threshold stimulation, motor threshold stimulation and sham EA groups. All patients undergo two periods in this study, including the treatment period (56 days) and the follow-up period (30 days). House-Brackmann grade and facial disability index scale will be measured as primary outcome before, 4 weeks treatment, after treatment and follow-up. The secondary outcome measures will be facial nerve electromyography (EMG) and blink reflex (BR) detection before and after treatments. Conclusion: This trial will evaluate the effect of different EA intensities for treating sequelae of PFP compared to sham EA. We hope this trial will provide effective treatment parameters for PFP sequelae. Trial registration: ClinicalTrials.gov Identifier: ChiCTR2200062310. Date: August 1, 2022.

show abstract

“…Three hours of repetitive somatosensory stimulation at the right index fingertip produced significant shifts in dipole location in the sensory cortex for both the index fingertip and the upper‐lip and improved 2‐point discrimination at the index fingertip and at the non‐stimulated upper lip (Muret et al, 2014, 2016). This finger‐to‐lip transfer appears to be specific to the face, as a subsequent study showed that two‐point discrimination was not improved on the forearm (Muret & Dinse, 2018).…”

Section: Introductionmentioning

confidence: 91%

Face–hand sensorimotor interactions revealed by afferent inhibition

Ramalho

Moly

Raffin

et al. 2021

Eur J of Neuroscience

View full text Add to dashboard Cite

Reorganization of the sensorimotor cortex following permanent (e.g., amputation) or temporary (e.g., local anaesthesia) deafferentation of the hand has revealed large‐scale plastic changes between the hand and face representations that are accompanied by perceptual correlates. The physiological mechanisms underlying this reorganization remain poorly understood. The aim of this study was to investigate sensorimotor interactions between the face and hand using an afferent inhibition transcranial magnetic stimulation protocol in which the motor evoked potential elicited by the magnetic pulse is inhibited when it is preceded by an afferent stimulus. We hypothesized that if face and hand representations in the sensorimotor cortex are functionally coupled, then electrocutaneous stimulation of the face would inhibit hand muscle motor responses. In two separate experiments, we delivered an electrocutaneous stimulus to either the skin over the right upper lip (Experiment 1) or right cheek (Experiment 2) and recorded muscular activity from the right first dorsal interosseous. Both lip and cheek stimulation inhibited right first dorsal interosseous motor evoked potentials. To investigate the specificity of this effect, we conducted two additional experiments in which electrocutaneous stimulation was applied to either the right forearm (Experiment 3) or right upper arm (Experiment 4). Forearm and upper arm stimulation also significantly inhibited the right first dorsal interosseous motor evoked potentials, but this inhibition was less robust than the inhibition associated with face stimulation. These findings provide the first evidence for face‐to‐hand afferent inhibition.

show abstract

Tactile learning transfer from the hand to the face but not to the forearm implies a special hand-face relationship

Cited by 11 publications

References 51 publications

Layer-Specific Vulnerability is a Mechanism of Topographic Map Aging

Layer-Specific Vulnerability is a Mechanism of Topographic Map Aging

Different intensities of electroacupuncture for peripheral facial paralysis sequelae: study protocol for a randomized placebo-controlled trial

Face–hand sensorimotor interactions revealed by afferent inhibition

Contact Info

Product

Resources

About