Frequency of the L1014F Mutation in the Sodium Channel Gene, in Culex quinquefasciatus (Diptera: Culicidae) Populations From Rural and Urban Areas of Yucatan State, Mexico

Abstract

Culex quinquefasciatus Say (Diptera: Culicidae) is a mosquito species that has attracted a lot of attention from a medical and veterinary point of view; however, little is known about the frequency of L1014F mutations that have been found in the sodium channel gene, with this being a target for DDT and pyrethroid insecticides. The distribution and frequency of the L1014F mutation in Cx. quinquefasciatus populations was determined in rural and urban areas of Yucatan, Mexico from January 2015 to March 2016. Nine hundred fifty adult females out of 17,727 immature states were collected and analyzed in all sites sampled (n = 10). Susceptible homozygotes were identified (L1014/L1014) in 12% (114/950), heterozygous individuals (F1014/L1014) in 34% (323/950), and mutated homozygotes (F1014/F1014) in 54% (513/950) during the dry and rainy seasons. In this work, study areas with a high frequency of L1014F mutation were identified. These findings may help guarantee a more effective and efficient use of the resources available for the control of this vector.

Occurrence of L1014F and L1014S mutations in insecticide resistant Culex quinquefasciatus from filariasis endemic districts of West Bengal, India

“…Presence of L1014F mutation in Cx . quinquefasciatus have been studied and reported from sub-Himalayan West Bengal in a previous study [ 42 ], India [ 21 ] and from different regions of the world [ 11 , 13 , 20 , 39 , 43 , 44 ]. However, L1014S mutation in the voltage-gated sodium channel gene in Cx .…”

Determination of insecticide resistence associated insensitive acetylcholinesterase in Culex quinquefasciatus, Say,1823 (Diptera: Culicidae) collected in Yucatán, Mexico

“…aegypti (López et al, 2014) and pyrethroid resistant alleles are known to be present in Cx. quinquefasciatus (Chi-Chim et al, 2018). The use of chemical products for pest control, both urban and agricultural, likely influences the tolerance to insecticides used in mosquito control programs in Mexico.…”